
Curing HIV: Seeking to Target and Clear Persistent Infection.
Publication
, Journal Article
Margolis, DM; Archin, NM; Cohen, MS; Eron, JJ; Ferrari, G; Garcia, JV; Gay, CL; Goonetilleke, N; Joseph, SB; Swanstrom, R; Turner, A-MW; Wahl, A
Published in: Cell
April 2, 2020
Human immunodeficiency virus type 1 (HIV-1) infection persists despite years of antiretroviral therapy (ART). To remove the stigma and burden of chronic infection, approaches to eradicate or cure HIV infection are desired. Attempts to augment ART with therapies that reverse viral latency, paired with immunotherapies to clear infection, have advanced into the clinic, but the field is still in its infancy. We review foundational studies and highlight new insights in HIV cure research. Together with advances in ART delivery and HIV prevention strategies, future therapies that clear HIV infection may relieve society of the affliction of the HIV pandemic.
Duke Scholars
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Published In
Cell
DOI
EISSN
1097-4172
Publication Date
April 2, 2020
Volume
181
Issue
1
Start / End Page
189 / 206
Location
United States
Related Subject Headings
- Virus Latency
- Immunotherapy
- Humans
- Haplorhini
- HIV-1
- HIV Infections
- Developmental Biology
- Chronic Disease
- Anti-HIV Agents
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Margolis, D. M., Archin, N. M., Cohen, M. S., Eron, J. J., Ferrari, G., Garcia, J. V., … Wahl, A. (2020). Curing HIV: Seeking to Target and Clear Persistent Infection. Cell, 181(1), 189–206. https://doi.org/10.1016/j.cell.2020.03.005
Margolis, David M., Nancie M. Archin, Myron S. Cohen, Joseph J. Eron, Guido Ferrari, J Victor Garcia, Cynthia L. Gay, et al. “Curing HIV: Seeking to Target and Clear Persistent Infection.” Cell 181, no. 1 (April 2, 2020): 189–206. https://doi.org/10.1016/j.cell.2020.03.005.
Margolis DM, Archin NM, Cohen MS, Eron JJ, Ferrari G, Garcia JV, et al. Curing HIV: Seeking to Target and Clear Persistent Infection. Cell. 2020 Apr 2;181(1):189–206.
Margolis, David M., et al. “Curing HIV: Seeking to Target and Clear Persistent Infection.” Cell, vol. 181, no. 1, Apr. 2020, pp. 189–206. Pubmed, doi:10.1016/j.cell.2020.03.005.
Margolis DM, Archin NM, Cohen MS, Eron JJ, Ferrari G, Garcia JV, Gay CL, Goonetilleke N, Joseph SB, Swanstrom R, Turner A-MW, Wahl A. Curing HIV: Seeking to Target and Clear Persistent Infection. Cell. 2020 Apr 2;181(1):189–206.

Published In
Cell
DOI
EISSN
1097-4172
Publication Date
April 2, 2020
Volume
181
Issue
1
Start / End Page
189 / 206
Location
United States
Related Subject Headings
- Virus Latency
- Immunotherapy
- Humans
- Haplorhini
- HIV-1
- HIV Infections
- Developmental Biology
- Chronic Disease
- Anti-HIV Agents
- Animals