How I approach hereditary hemolytic anemia and splenectomy.
Publication
, Journal Article
Rothman, JA; Stevens, JL; Gray, FL; Kalfa, TA
Published in: Pediatr Blood Cancer
November 2020
Hereditary hemolytic anemias (HHA) are a heterogeneous group of anemias associated with decreased red cell survival. While there can be clinical benefit of splenectomy in many cases, splenectomy is not appropriate for all types of HHA. Additionally, there are significant risks during and following splenectomy including surgical risks, postsplenectomy sepsis, and thrombotic complications. This review discusses the diagnostic approach to HHA as well as the role of splenectomy in the management. Surgical approaches and outcomes for total and partial splenectomy are discussed.
Duke Scholars
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Published In
Pediatr Blood Cancer
DOI
EISSN
1545-5017
Publication Date
November 2020
Volume
67
Issue
11
Start / End Page
e28337
Location
United States
Related Subject Headings
- Thrombosis
- Splenectomy
- Referral and Consultation
- Prognosis
- Postoperative Complications
- Oncology & Carcinogenesis
- Male
- Humans
- Female
- Child, Preschool
Citation
APA
Chicago
ICMJE
MLA
NLM
Rothman, J. A., Stevens, J. L., Gray, F. L., & Kalfa, T. A. (2020). How I approach hereditary hemolytic anemia and splenectomy. Pediatr Blood Cancer, 67(11), e28337. https://doi.org/10.1002/pbc.28337
Rothman, Jennifer A., Jenny L. Stevens, Fabienne L. Gray, and Theodosia A. Kalfa. “How I approach hereditary hemolytic anemia and splenectomy.” Pediatr Blood Cancer 67, no. 11 (November 2020): e28337. https://doi.org/10.1002/pbc.28337.
Rothman JA, Stevens JL, Gray FL, Kalfa TA. How I approach hereditary hemolytic anemia and splenectomy. Pediatr Blood Cancer. 2020 Nov;67(11):e28337.
Rothman, Jennifer A., et al. “How I approach hereditary hemolytic anemia and splenectomy.” Pediatr Blood Cancer, vol. 67, no. 11, Nov. 2020, p. e28337. Pubmed, doi:10.1002/pbc.28337.
Rothman JA, Stevens JL, Gray FL, Kalfa TA. How I approach hereditary hemolytic anemia and splenectomy. Pediatr Blood Cancer. 2020 Nov;67(11):e28337.
Published In
Pediatr Blood Cancer
DOI
EISSN
1545-5017
Publication Date
November 2020
Volume
67
Issue
11
Start / End Page
e28337
Location
United States
Related Subject Headings
- Thrombosis
- Splenectomy
- Referral and Consultation
- Prognosis
- Postoperative Complications
- Oncology & Carcinogenesis
- Male
- Humans
- Female
- Child, Preschool