Skip to main content
Journal cover image

Recent advances in genome editing and creation of genetically modified pigs.

Publication ,  Journal Article
Butler, JR; Ladowski, JM; Martens, GR; Tector, M; Tector, AJ
Published in: International journal of surgery (London, England)
November 2015

The field of xenotransplantation is benefiting greatly from recent advances in genetic engineering. The efficiency and pace with which new model animals are being created has dramatically sped progress towards clinical relevance. Endonuclease-driven genome editing now allows for the efficient generation of targeted genetic alterations. Herein we review the available methods of genetic engineering that have been successfully employed to create genetically modified pigs.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

International journal of surgery (London, England)

DOI

EISSN

1743-9159

ISSN

1743-9191

Publication Date

November 2015

Volume

23

Issue

Pt B

Start / End Page

217 / 222

Related Subject Headings

  • Transplantation, Heterologous
  • Swine
  • Surgery
  • Genome
  • Genetic Engineering
  • Animals, Genetically Modified
  • Animals
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Butler, J. R., Ladowski, J. M., Martens, G. R., Tector, M., & Tector, A. J. (2015). Recent advances in genome editing and creation of genetically modified pigs. International Journal of Surgery (London, England), 23(Pt B), 217–222. https://doi.org/10.1016/j.ijsu.2015.07.684
Butler, James R., Joseph M. Ladowski, Gregory R. Martens, Matthew Tector, and A Joseph Tector. “Recent advances in genome editing and creation of genetically modified pigs.International Journal of Surgery (London, England) 23, no. Pt B (November 2015): 217–22. https://doi.org/10.1016/j.ijsu.2015.07.684.
Butler JR, Ladowski JM, Martens GR, Tector M, Tector AJ. Recent advances in genome editing and creation of genetically modified pigs. International journal of surgery (London, England). 2015 Nov;23(Pt B):217–22.
Butler, James R., et al. “Recent advances in genome editing and creation of genetically modified pigs.International Journal of Surgery (London, England), vol. 23, no. Pt B, Nov. 2015, pp. 217–22. Epmc, doi:10.1016/j.ijsu.2015.07.684.
Butler JR, Ladowski JM, Martens GR, Tector M, Tector AJ. Recent advances in genome editing and creation of genetically modified pigs. International journal of surgery (London, England). 2015 Nov;23(Pt B):217–222.
Journal cover image

Published In

International journal of surgery (London, England)

DOI

EISSN

1743-9159

ISSN

1743-9191

Publication Date

November 2015

Volume

23

Issue

Pt B

Start / End Page

217 / 222

Related Subject Headings

  • Transplantation, Heterologous
  • Swine
  • Surgery
  • Genome
  • Genetic Engineering
  • Animals, Genetically Modified
  • Animals
  • 3202 Clinical sciences
  • 1103 Clinical Sciences