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Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking

Publication ,  Journal Article
Gedye, C; Sachchithananthan, M; Leonard, R; Jeffree, RL; Buckland, ME; Ziegler, DS; Graeber, MB; Day, BW; McDonald, KL; Lasocki, A; Back, M ...
Published in: Neuro-Oncology Practice
January 31, 2020

Background: A key component of cancer research is the availability of clinical samples with appropriately annotated clinical data. Biobanks facilitate research by collecting/storing various types of clinical samples for research. Brain Cancer Biobanking Australia (BCBA) was established to facilitate the networking of brain cancer biobanking operations Australia-wide. Maximizing biospecimen utility in a networked biobanking environment requires the standardization of procedures and data across different sites. The aim of this research was to scope and develop a recommended clinical annotation dataset both for pediatric and adult brain cancer biobanks. Methods: A multidisciplinary working group consisting of members from the BCBA Consortium was established to develop clinical dataset recommendations for brain cancer biobanks. A literature search was undertaken to identify any published clinical dataset recommendations for brain cancer biobanks. An audit of data items collected and stored by BCBA member biobanks was also conducted to survey current clinical data collection practices across the BCBA network. Results: BCBA has developed a clinical annotation dataset recommendation for pediatric and adult brain cancer biobanks. The clinical dataset recommendation has 5 clinical data categories: demographic, clinical and radiological diagnosis and surgery, neuropathological diagnosis, patient treatment, and patient follow-up. The data fields have been categorized into 1 of 3 tiers; essential, preferred, and comprehensive. This enables biobanks and researchers to prioritize appropriately where resources are limited. Conclusion: This dataset can be used to guide the integration of data from multiple existing biobanks for research studies and for planning prospective brain cancer biobanking activities.

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Published In

Neuro-Oncology Practice

DOI

EISSN

2054-2585

ISSN

2054-2577

Publication Date

January 31, 2020

Volume

7

Issue

1

Start / End Page

31 / 37
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gedye, C., Sachchithananthan, M., Leonard, R., Jeffree, R. L., Buckland, M. E., Ziegler, D. S., … Nowak, A. K. (2020). Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking. Neuro-Oncology Practice, 7(1), 31–37. https://doi.org/10.1093/nop/npz036
Gedye, C., M. Sachchithananthan, R. Leonard, R. L. Jeffree, M. E. Buckland, D. S. Ziegler, M. B. Graeber, et al. “Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking.” Neuro-Oncology Practice 7, no. 1 (January 31, 2020): 31–37. https://doi.org/10.1093/nop/npz036.
Gedye C, Sachchithananthan M, Leonard R, Jeffree RL, Buckland ME, Ziegler DS, et al. Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking. Neuro-Oncology Practice. 2020 Jan 31;7(1):31–7.
Gedye, C., et al. “Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking.” Neuro-Oncology Practice, vol. 7, no. 1, Jan. 2020, pp. 31–37. Scopus, doi:10.1093/nop/npz036.
Gedye C, Sachchithananthan M, Leonard R, Jeffree RL, Buckland ME, Ziegler DS, Graeber MB, Day BW, McDonald KL, Lasocki A, Back M, Besser M, Boyd A, Byrne J, Cher L, Cook R, Day J, Davidson A, Devereux L, Dexter M, Donnelly R, Drummond K, Eckstein L, Gan H, Garrick T, Gottardo N, Harper C, Johns T, Khasraw M, Kichenadasse G, Eng-Siew K, Lipworth W, Ludlow L, Moore A, Munoz L, Nahar N, Olson S, Ormsby R, Parkinson J, Partanen A, Raymond E, Reddel R, Robbins P, Rosenthal M, Saunus J, Shivalingam B, Simes J, Stringer B, Thorne H, Vajdic C, Varikatt W, Walker D, Wheeler H, White D, Yip S, Nowak AK. Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking. Neuro-Oncology Practice. 2020 Jan 31;7(1):31–37.
Journal cover image

Published In

Neuro-Oncology Practice

DOI

EISSN

2054-2585

ISSN

2054-2577

Publication Date

January 31, 2020

Volume

7

Issue

1

Start / End Page

31 / 37