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Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers.

Publication ,  Journal Article
Liu, W; Huang, J; Lin, Y; Cai, C; Zhao, Y; Teng, Y; Mo, J; Xue, L; Liu, L; Xu, W; Guo, X; Zhang, Y; Zhang, JJ
Published in: Indoor air
January 2021

Negative ion air purifiers (NIAPs), as a less costly alternative to the HEPA filtration, have been increasingly deployed in China and potentially elsewhere. While reducing indoor concentrations of fine particulate matter (PM2.5 ), NIAPs generate massive amounts of negative ions that may be of health concern. We performed week-long interventions with NIAPs in the dormitories of 56 healthy college students living in Beijing. In a randomized order, each student underwent a true and a sham NIAP session. Cardiorespiratory outcomes were measured before and after each session. The use of true NIAPs reduced indoor PM2.5 concentrations significantly, while notably increased negative ion levels. Increases in PM2.5 and negative ion (NI) exposure were independently associated with increased urinary concentration of malondialdehyde, a biomarker of systemic oxidative stress, resulting in a null net effect of NIAP on malondialdehyde. Likewise, no significant net effects of NIAPs were observed for other outcomes indicative of lung function, vascular tone, arterial stiffness, and inflammation. Our findings suggest that negative ions, possibly along with their reaction products with the room air constituents, adversely affect health. The downsides do not support the use of NIAPs as a health-based mitigation strategy to reduce PM2.5 exposure, especially in residences with PM2.5 concentrations that are not extremely high.

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Published In

Indoor air

DOI

EISSN

1600-0668

ISSN

0905-6947

Publication Date

January 2021

Volume

31

Issue

1

Start / End Page

220 / 228

Related Subject Headings

  • Young Adult
  • Particulate Matter
  • Particle Size
  • Oxidative Stress
  • Ions
  • Inflammation
  • Humans
  • Housing
  • Filtration
  • Environmental Monitoring
 

Citation

APA
Chicago
ICMJE
MLA
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Liu, W., Huang, J., Lin, Y., Cai, C., Zhao, Y., Teng, Y., … Zhang, J. J. (2021). Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers. Indoor Air, 31(1), 220–228. https://doi.org/10.1111/ina.12728
Liu, Wei, Jing Huang, Yan Lin, Chaorui Cai, Yan Zhao, Yanbo Teng, Jinhan Mo, et al. “Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers.Indoor Air 31, no. 1 (January 2021): 220–28. https://doi.org/10.1111/ina.12728.
Liu W, Huang J, Lin Y, Cai C, Zhao Y, Teng Y, et al. Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers. Indoor air. 2021 Jan;31(1):220–8.
Liu, Wei, et al. “Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers.Indoor Air, vol. 31, no. 1, Jan. 2021, pp. 220–28. Epmc, doi:10.1111/ina.12728.
Liu W, Huang J, Lin Y, Cai C, Zhao Y, Teng Y, Mo J, Xue L, Liu L, Xu W, Guo X, Zhang Y, Zhang JJ. Negative ions offset cardiorespiratory benefits of PM2.5 reduction from residential use of negative ion air purifiers. Indoor air. 2021 Jan;31(1):220–228.
Journal cover image

Published In

Indoor air

DOI

EISSN

1600-0668

ISSN

0905-6947

Publication Date

January 2021

Volume

31

Issue

1

Start / End Page

220 / 228

Related Subject Headings

  • Young Adult
  • Particulate Matter
  • Particle Size
  • Oxidative Stress
  • Ions
  • Inflammation
  • Humans
  • Housing
  • Filtration
  • Environmental Monitoring