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Acoustic Signatures of Left Ventricular Assist Device Thrombosis.

Publication ,  Journal Article
Patel, P; Mainsah, B; Milano, CA; Nowacek, DP; Collins, L; Karra, R
Published in: J Eng Sci Med Diagn Ther
May 2019

Left ventricular assist devices (LVADs) are life-saving, surgically implanted mechanical heart pumps used to treat patients with advanced heart failure (HF). While life-saving, LVAD support is associated with a high incidence of complications, making early recognition and management of LVAD complications a critical need. Blood clot formation within the LVAD, known as LVAD thrombosis, is a catastrophic complication of LVAD therapy that often requires LVAD exchange due to delayed diagnosis and treatment. Using digital stethoscopes, we identified differences in acoustic spectra from two patients presenting with LVAD thrombosis compared with normally functioning LVAD pumps within the same patient. Importantly, these acoustic changes were present even in the absence of typical signs of HF that are often present in LVAD thrombosis patients. Our work suggests that acoustic spectral analysis of digital stethoscope signals could be used for early detection and mitigation of LVAD complications.

Duke Scholars

Published In

J Eng Sci Med Diagn Ther

DOI

EISSN

2572-7966

Publication Date

May 2019

Volume

2

Issue

2

Start / End Page

0245011 / 0245014

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Patel, P., Mainsah, B., Milano, C. A., Nowacek, D. P., Collins, L., & Karra, R. (2019). Acoustic Signatures of Left Ventricular Assist Device Thrombosis. J Eng Sci Med Diagn Ther, 2(2), 0245011–0245014. https://doi.org/10.1115/1.4041529
Patel, Priyesh, Boyla Mainsah, Carmelo A. Milano, Douglas P. Nowacek, Leslie Collins, and Ravi Karra. “Acoustic Signatures of Left Ventricular Assist Device Thrombosis.J Eng Sci Med Diagn Ther 2, no. 2 (May 2019): 0245011–14. https://doi.org/10.1115/1.4041529.
Patel P, Mainsah B, Milano CA, Nowacek DP, Collins L, Karra R. Acoustic Signatures of Left Ventricular Assist Device Thrombosis. J Eng Sci Med Diagn Ther. 2019 May;2(2):0245011–4.
Patel, Priyesh, et al. “Acoustic Signatures of Left Ventricular Assist Device Thrombosis.J Eng Sci Med Diagn Ther, vol. 2, no. 2, May 2019, pp. 0245011–14. Pubmed, doi:10.1115/1.4041529.
Patel P, Mainsah B, Milano CA, Nowacek DP, Collins L, Karra R. Acoustic Signatures of Left Ventricular Assist Device Thrombosis. J Eng Sci Med Diagn Ther. 2019 May;2(2):0245011–0245014.

Published In

J Eng Sci Med Diagn Ther

DOI

EISSN

2572-7966

Publication Date

May 2019

Volume

2

Issue

2

Start / End Page

0245011 / 0245014

Location

United States