Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Injectable biomaterials for treatment of glioblastoma.

Publication ,  Journal Article
Anderson, AR; Segura, T
Published in: Advanced materials interfaces
October 2020

Despite ongoing advancements in the field of medicine, glioblastoma multiforme (GBM) is presently incurable, making this advanced brain tumor the deadliest tumor type in the central nervous system. The primary treatment strategies for GBM (i.e. surgical resection, radiation therapy, chemotherapy, and newly incorporated targeted therapies) fail to overcome the challenging characteristics of highly aggressive GBM tumors and are presently given with the goal of increasing the quality of life for patients. With the aim of creating effective treatment solutions, research has shifted toward utilizing injectable biomaterial adjuncts to minimize invasiveness of treatment, provide spatiotemporal control of therapeutic delivery, and engage with cells through material-cell interfaces. This review aims to summarize the limitations of the current standard of care for GBM, discuss how these limitations can be addressed by local employment of injectable biomaterial systems, and highlight developments in the field of biomaterials for these applications.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Advanced materials interfaces

DOI

EISSN

2196-7350

ISSN

2196-7350

Publication Date

October 2020

Volume

7

Issue

20

Start / End Page

2001055

Related Subject Headings

  • 5104 Condensed matter physics
  • 4016 Materials engineering
  • 3403 Macromolecular and materials chemistry
  • 0912 Materials Engineering
  • 0306 Physical Chemistry (incl. Structural)
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Anderson, A. R., & Segura, T. (2020). Injectable biomaterials for treatment of glioblastoma. Advanced Materials Interfaces, 7(20), 2001055. https://doi.org/10.1002/admi.202001055
Anderson, Alexa R., and Tatiana Segura. “Injectable biomaterials for treatment of glioblastoma.Advanced Materials Interfaces 7, no. 20 (October 2020): 2001055. https://doi.org/10.1002/admi.202001055.
Anderson AR, Segura T. Injectable biomaterials for treatment of glioblastoma. Advanced materials interfaces. 2020 Oct;7(20):2001055.
Anderson, Alexa R., and Tatiana Segura. “Injectable biomaterials for treatment of glioblastoma.Advanced Materials Interfaces, vol. 7, no. 20, Oct. 2020, p. 2001055. Epmc, doi:10.1002/admi.202001055.
Anderson AR, Segura T. Injectable biomaterials for treatment of glioblastoma. Advanced materials interfaces. 2020 Oct;7(20):2001055.
Journal cover image

Published In

Advanced materials interfaces

DOI

EISSN

2196-7350

ISSN

2196-7350

Publication Date

October 2020

Volume

7

Issue

20

Start / End Page

2001055

Related Subject Headings

  • 5104 Condensed matter physics
  • 4016 Materials engineering
  • 3403 Macromolecular and materials chemistry
  • 0912 Materials Engineering
  • 0306 Physical Chemistry (incl. Structural)