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Obesity-related asthma in children: A role for vitamin D.

Publication ,  Journal Article
O'Sullivan, BP; James, L; Majure, JM; Bickel, S; Phan, L-T; Serrano Gonzalez, M; Staples, H; Tam-Williams, J; Lang, J; Snowden, J ...
Published in: Pediatr Pulmonol
February 2021

Excess adipose tissue predisposes to an enhanced inflammatory state and can contribute to the pathogenesis and severity of asthma. Vitamin D has anti-inflammatory properties and low-serum levels are seen in children with asthma and in children with obesity. Here we review the intersection of asthma, obesity, and hypovitaminosis D in children. Supplementation with vitamin D has been proposed as a simple, safe, and inexpensive adjunctive therapy in a number of disease states. However, little research has examined the pharmacokinetics of vitamin D and its therapeutic potential in children who suffer from obesity-related asthma.

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Published In

Pediatr Pulmonol

DOI

EISSN

1099-0496

Publication Date

February 2021

Volume

56

Issue

2

Start / End Page

354 / 361

Location

United States

Related Subject Headings

  • Vitamins
  • Vitamin D Deficiency
  • Vitamin D
  • Respiratory System
  • Obesity
  • Inflammation
  • Humans
  • Dietary Supplements
  • Child
  • Asthma
 

Citation

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O’Sullivan, B. P., James, L., Majure, J. M., Bickel, S., Phan, L.-T., Serrano Gonzalez, M., … IDeA States Pediatric Clinical Trials Network. (2021). Obesity-related asthma in children: A role for vitamin D. Pediatr Pulmonol, 56(2), 354–361. https://doi.org/10.1002/ppul.25053
O’Sullivan, Brian P., Laura James, Joseph M. Majure, Scott Bickel, Ly-Thao Phan, Monica Serrano Gonzalez, Heather Staples, et al. “Obesity-related asthma in children: A role for vitamin D.Pediatr Pulmonol 56, no. 2 (February 2021): 354–61. https://doi.org/10.1002/ppul.25053.
O’Sullivan BP, James L, Majure JM, Bickel S, Phan L-T, Serrano Gonzalez M, et al. Obesity-related asthma in children: A role for vitamin D. Pediatr Pulmonol. 2021 Feb;56(2):354–61.
O’Sullivan, Brian P., et al. “Obesity-related asthma in children: A role for vitamin D.Pediatr Pulmonol, vol. 56, no. 2, Feb. 2021, pp. 354–61. Pubmed, doi:10.1002/ppul.25053.
O’Sullivan BP, James L, Majure JM, Bickel S, Phan L-T, Serrano Gonzalez M, Staples H, Tam-Williams J, Lang J, Snowden J, IDeA States Pediatric Clinical Trials Network. Obesity-related asthma in children: A role for vitamin D. Pediatr Pulmonol. 2021 Feb;56(2):354–361.
Journal cover image

Published In

Pediatr Pulmonol

DOI

EISSN

1099-0496

Publication Date

February 2021

Volume

56

Issue

2

Start / End Page

354 / 361

Location

United States

Related Subject Headings

  • Vitamins
  • Vitamin D Deficiency
  • Vitamin D
  • Respiratory System
  • Obesity
  • Inflammation
  • Humans
  • Dietary Supplements
  • Child
  • Asthma