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Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature.

Publication ,  Journal Article
Knisely, A; Wu, J; Kaplan, SJ; Zhou, ZN; Melamed, A; Tergas, AI; St Clair, CM; Hou, JY; Khoury-Collado, F; Huang, YY-C; Hershman, DL; Wright, JD
Published in: Cancer investigation
September 2020

Coronavirus 2019 (COVID-19) has spread rapidly around the world to become a global pandemic. There is limited data on the impact of COVID-19 among patients with cancer.A systematic review was performed to determine outcomes of adult patients with cancer affected by coronavirus infections, specifically SARS, MERS, and COVID-19. Studies were independently screened by two reviewers and assessed for quality and bias. Outcomes measured included study characteristics, cancer type, phase of care at the time of diagnosis, and clinical presentation. Morbidity and mortality outcomes were analyzed to assess the severity of infection as compared to the general population.A total of 19 studies with 110 patients were included. Of these, 66.4% had COVID-19 infections, 32.7% MERS and only one patient with SARS. The majority of COVID-19 studies were based on studies in China. There was a 56.6% rate of a severe event, including ICU admission or requiring mechanical ventilation, with an overall 44.5% fatality rate.Patients with cancer with coronavirus infections may be more susceptible to higher morbidity and mortality.

Duke Scholars

Published In

Cancer investigation

DOI

EISSN

1532-4192

ISSN

0735-7907

Publication Date

September 2020

Volume

38

Issue

8-9

Start / End Page

436 / 444

Related Subject Headings

  • Severe Acute Respiratory Syndrome
  • Pneumonia, Viral
  • Pandemics
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • Coronavirus Infections
  • China
  • COVID-19
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Knisely, A., Wu, J., Kaplan, S. J., Zhou, Z. N., Melamed, A., Tergas, A. I., … Wright, J. D. (2020). Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature. Cancer Investigation, 38(8–9), 436–444. https://doi.org/10.1080/07357907.2020.1809668
Knisely, Anne, Jenny Wu, Samantha J. Kaplan, Zhen Ni Zhou, Alexander Melamed, Ana I. Tergas, Caryn M. St Clair, et al. “Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature.Cancer Investigation 38, no. 8–9 (September 2020): 436–44. https://doi.org/10.1080/07357907.2020.1809668.
Knisely A, Wu J, Kaplan SJ, Zhou ZN, Melamed A, Tergas AI, et al. Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature. Cancer investigation. 2020 Sep;38(8–9):436–44.
Knisely, Anne, et al. “Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature.Cancer Investigation, vol. 38, no. 8–9, Sept. 2020, pp. 436–44. Epmc, doi:10.1080/07357907.2020.1809668.
Knisely A, Wu J, Kaplan SJ, Zhou ZN, Melamed A, Tergas AI, St Clair CM, Hou JY, Khoury-Collado F, Huang YY-C, Hershman DL, Wright JD. Coronavirus Spectrum Infections (COVID-19, MERS, SARS) in Cancer Patients: A Systematic Review of the Literature. Cancer investigation. 2020 Sep;38(8–9):436–444.

Published In

Cancer investigation

DOI

EISSN

1532-4192

ISSN

0735-7907

Publication Date

September 2020

Volume

38

Issue

8-9

Start / End Page

436 / 444

Related Subject Headings

  • Severe Acute Respiratory Syndrome
  • Pneumonia, Viral
  • Pandemics
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • Coronavirus Infections
  • China
  • COVID-19
  • Adult