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Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence.

Publication ,  Journal Article
Kang, L; Li, J; Zhao, T; Xiao, F; Tang, X; Thilmony, R; He, S; Zhou, J-M
Published in: Proceedings of the National Academy of Sciences of the United States of America
March 2003

It is poorly understood why a particular plant species is resistant to the vast majority of potential pathogens that infect other plant species, a phenomenon referred to as "nonhost" resistance. Here, we show that Arabidopsis NHO1, encoding a glycerol kinase, is required for resistance to and induced by Pseudomonas syringae isolates from bean and tobacco. NHO1 is also required for resistance to the fungal pathogen Botrytis cinerea, indicating that NHO1 is not limited to bacterial resistance. Strikingly, P. s. pv. tomato DC3000, an isolate fully virulent on Arabidopsis, actively suppressed the NHO1 expression. This suppression is abolished in coi1 plants, indicating that DC3000 required an intact jasmonic acid signaling pathway in the plant to suppress NHO1 expression. Constitutive overexpression of NHO1 led to enhanced resistance to this otherwise virulent bacterium. The presence of avrB in DC3000, which activates a cultivar-specific "gene-for-gene" resistance in Arabidopsis, restored the induction of NHO1 expression. Thus, NHO1 is deployed for both general and specific resistance in Arabidopsis and targeted by the bacterium for parasitism.

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Published In

Proceedings of the National Academy of Sciences of the United States of America

DOI

EISSN

1091-6490

ISSN

0027-8424

Publication Date

March 2003

Volume

100

Issue

6

Start / End Page

3519 / 3524

Related Subject Headings

  • Virulence
  • Sequence Homology, Amino Acid
  • Pseudomonas
  • Plant Diseases
  • Molecular Sequence Data
  • Glycerol Kinase
  • Genetic Complementation Test
  • Genes, Plant
  • Gene Expression
  • DNA, Plant
 

Citation

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Kang, L., Li, J., Zhao, T., Xiao, F., Tang, X., Thilmony, R., … Zhou, J.-M. (2003). Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence. Proceedings of the National Academy of Sciences of the United States of America, 100(6), 3519–3524. https://doi.org/10.1073/pnas.0637377100
Kang, Li, Jianxiong Li, Tiehan Zhao, Fangming Xiao, Xiaoyan Tang, Roger Thilmony, ShengYang He, and Jian-Min Zhou. “Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence.Proceedings of the National Academy of Sciences of the United States of America 100, no. 6 (March 2003): 3519–24. https://doi.org/10.1073/pnas.0637377100.
Kang L, Li J, Zhao T, Xiao F, Tang X, Thilmony R, et al. Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2003 Mar;100(6):3519–24.
Kang, Li, et al. “Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence.Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 6, Mar. 2003, pp. 3519–24. Epmc, doi:10.1073/pnas.0637377100.
Kang L, Li J, Zhao T, Xiao F, Tang X, Thilmony R, He S, Zhou J-M. Interplay of the Arabidopsis nonhost resistance gene NHO1 with bacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2003 Mar;100(6):3519–3524.
Journal cover image

Published In

Proceedings of the National Academy of Sciences of the United States of America

DOI

EISSN

1091-6490

ISSN

0027-8424

Publication Date

March 2003

Volume

100

Issue

6

Start / End Page

3519 / 3524

Related Subject Headings

  • Virulence
  • Sequence Homology, Amino Acid
  • Pseudomonas
  • Plant Diseases
  • Molecular Sequence Data
  • Glycerol Kinase
  • Genetic Complementation Test
  • Genes, Plant
  • Gene Expression
  • DNA, Plant