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Type III protein secretion mechanism in mammalian and plant pathogens.

Publication ,  Journal Article
He, SY; Nomura, K; Whittam, TS
Published in: Biochimica et biophysica acta
November 2004

The type III protein secretion system (TTSS) is a complex organelle in the envelope of many Gram-negative bacteria; it delivers potentially hundreds of structurally diverse bacterial virulence proteins into plant and animal cells to modulate host cellular functions. Recent studies have revealed several basic features of this secretion system, including assembly of needle/pilus-like secretion structures, formation of putative translocation pores in the host membrane, recognition of N-terminal/5' mRNA-based secretion signals, and requirement of small chaperone proteins for optimal delivery and/or expression of effector proteins. Although most of our knowledge about the TTSS is derived from studies of mammalian pathogenic bacteria, similar and unique features are learned from studies of plant pathogenic bacteria. Here, we summarize the most salient aspects of the TTSS, with special emphasis on recent findings.

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Published In

Biochimica et biophysica acta

DOI

EISSN

1878-2434

ISSN

0006-3002

Publication Date

November 2004

Volume

1694

Issue

1-3

Start / End Page

181 / 206

Related Subject Headings

  • Yersinia
  • Pseudomonas
  • Protein Transport
  • Plant Diseases
  • Phylogeny
  • Membrane Transport Proteins
  • Mammals
  • Gram-Negative Bacterial Infections
  • Gram-Negative Bacteria
  • Bacterial Proteins
 

Citation

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He, S. Y., Nomura, K., & Whittam, T. S. (2004). Type III protein secretion mechanism in mammalian and plant pathogens. Biochimica et Biophysica Acta, 1694(1–3), 181–206. https://doi.org/10.1016/j.bbamcr.2004.03.011
He, Sheng Yang, Kinya Nomura, and Thomas S. Whittam. “Type III protein secretion mechanism in mammalian and plant pathogens.Biochimica et Biophysica Acta 1694, no. 1–3 (November 2004): 181–206. https://doi.org/10.1016/j.bbamcr.2004.03.011.
He SY, Nomura K, Whittam TS. Type III protein secretion mechanism in mammalian and plant pathogens. Biochimica et biophysica acta. 2004 Nov;1694(1–3):181–206.
He, Sheng Yang, et al. “Type III protein secretion mechanism in mammalian and plant pathogens.Biochimica et Biophysica Acta, vol. 1694, no. 1–3, Nov. 2004, pp. 181–206. Epmc, doi:10.1016/j.bbamcr.2004.03.011.
He SY, Nomura K, Whittam TS. Type III protein secretion mechanism in mammalian and plant pathogens. Biochimica et biophysica acta. 2004 Nov;1694(1–3):181–206.

Published In

Biochimica et biophysica acta

DOI

EISSN

1878-2434

ISSN

0006-3002

Publication Date

November 2004

Volume

1694

Issue

1-3

Start / End Page

181 / 206

Related Subject Headings

  • Yersinia
  • Pseudomonas
  • Protein Transport
  • Plant Diseases
  • Phylogeny
  • Membrane Transport Proteins
  • Mammals
  • Gram-Negative Bacterial Infections
  • Gram-Negative Bacteria
  • Bacterial Proteins