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Whole Mount In Situ Hybridization in Murine Tissues.

Publication ,  Journal Article
Sharma, D; Hilton, MJ; Karner, CM
Published in: Methods Mol Biol
2021

Whole mount in situ hybridization is a sensitive method used to characterize the spatial and temporal expression of RNA transcripts throughout an entire tissue. This method is an excellent tool for studying gene expression during embryonic development. Here, we describe a procedure for digoxigenin labeled in situ hybridization on whole embryos.

Duke Scholars

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2021

Volume

2230

Start / End Page

367 / 376

Location

United States

Related Subject Headings

  • RNA Probes
  • Pregnancy
  • Mice
  • In Situ Hybridization
  • Gene Expression Regulation, Developmental
  • Female
  • Embryonic Development
  • Embryo, Mammalian
  • Digoxigenin
  • Developmental Biology
 

Citation

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ICMJE
MLA
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Sharma, D., Hilton, M. J., & Karner, C. M. (2021). Whole Mount In Situ Hybridization in Murine Tissues. Methods Mol Biol, 2230, 367–376. https://doi.org/10.1007/978-1-0716-1028-2_22
Sharma, Deepika, Matthew J. Hilton, and Courtney M. Karner. “Whole Mount In Situ Hybridization in Murine Tissues.Methods Mol Biol 2230 (2021): 367–76. https://doi.org/10.1007/978-1-0716-1028-2_22.
Sharma D, Hilton MJ, Karner CM. Whole Mount In Situ Hybridization in Murine Tissues. Methods Mol Biol. 2021;2230:367–76.
Sharma, Deepika, et al. “Whole Mount In Situ Hybridization in Murine Tissues.Methods Mol Biol, vol. 2230, 2021, pp. 367–76. Pubmed, doi:10.1007/978-1-0716-1028-2_22.
Sharma D, Hilton MJ, Karner CM. Whole Mount In Situ Hybridization in Murine Tissues. Methods Mol Biol. 2021;2230:367–376.

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2021

Volume

2230

Start / End Page

367 / 376

Location

United States

Related Subject Headings

  • RNA Probes
  • Pregnancy
  • Mice
  • In Situ Hybridization
  • Gene Expression Regulation, Developmental
  • Female
  • Embryonic Development
  • Embryo, Mammalian
  • Digoxigenin
  • Developmental Biology