
Synergism of chlorpyrifos against the German cockroach, Blattella germanica.
Of fifteen compounds tested as synergists for chlorpyrifos against susceptible and resistant strains of Blattella germanica, the German cockroach, eleven were active against the resistant strain but only seven were synergistic against the susceptible strain. Overall, the most effective synergist was S,S,S-tributyl phosphorotrithioate (DEF) followed by phenyl saligenin cyclic phosphonate (PSCP) and two substituted N,N-dimethylcarbamates: SK-102 and SK-37. The most effective synergist for overcoming chlorpyrifos resistance was SK-37 which reduced the resistance ratio by 3.2-fold. Four other synergists which reduced chlorpyrifos resistance, in order of their effectiveness, were: SK-102 > PSCP > DEF > tridiphane. The potential usefulness of these synergists for German cockroach control is discussed.
Duke Scholars
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Related Subject Headings
- Tropical Medicine
- Insecticides
- Insecticide Resistance
- Drug Synergism
- Cockroaches
- Chlorpyrifos
- Animals
- 11 Medical and Health Sciences
- 07 Agricultural and Veterinary Sciences
- 06 Biological Sciences
Citation

Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Tropical Medicine
- Insecticides
- Insecticide Resistance
- Drug Synergism
- Cockroaches
- Chlorpyrifos
- Animals
- 11 Medical and Health Sciences
- 07 Agricultural and Veterinary Sciences
- 06 Biological Sciences