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kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.

Publication ,  Journal Article
Scott, JG; Dong, K
Published in: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
October 1994

The phenomenon of knockdown resistance (kdr) was first noted in the housefly (Musca domestica), and has subsequently be found (i.e. kdr-type resistance) in several other insect pests including the German cockroach (Blattella germanica). This type of resistance causes insensitivity of the nervous system to pyrethroids, DDT and a limited number of sodium channel neurotoxins. In the German cockroach, kdr-type resistance is incompletely recessive, monogenic and not sex linked or due to cytoplasmic factors. Additionally, kdr-type resistance is not associated with a change in sodium channel density. kdr or kdr-type loci are tightly linked or identical to the para-homologous sodium channel locus in German cockroach, housefly and tobacco budworm (Heliothis virescens), suggesting that kdr and kdr-type resistance are due to mutations in the para-homologous sodium channel gene. kdr-Type resistance in the German cockroach appears similar, although not necessarily identical, to kdr in houseflies.

Duke Scholars

Published In

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

DOI

EISSN

1879-1107

ISSN

1096-4959

Publication Date

October 1994

Volume

109

Issue

2-3

Start / End Page

191 / 198

Related Subject Headings

  • Pyrethrins
  • Neurotoxins
  • Genes, Recessive
  • Drug Resistance, Multiple
  • DDT
  • Cockroaches
  • Biochemistry & Molecular Biology
  • Animals
  • 3109 Zoology
  • 3101 Biochemistry and cell biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Scott, J. G., & Dong, K. (1994). kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology, 109(2–3), 191–198. https://doi.org/10.1016/0305-0491(94)90002-7
Scott, J. G., and K. Dong. “kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology 109, no. 2–3 (October 1994): 191–98. https://doi.org/10.1016/0305-0491(94)90002-7.
Scott JG, Dong K. kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica. Comparative biochemistry and physiology Part B, Biochemistry & molecular biology. 1994 Oct;109(2–3):191–8.
Scott, J. G., and K. Dong. “kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology, vol. 109, no. 2–3, Oct. 1994, pp. 191–98. Epmc, doi:10.1016/0305-0491(94)90002-7.
Scott JG, Dong K. kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica. Comparative biochemistry and physiology Part B, Biochemistry & molecular biology. 1994 Oct;109(2–3):191–198.
Journal cover image

Published In

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

DOI

EISSN

1879-1107

ISSN

1096-4959

Publication Date

October 1994

Volume

109

Issue

2-3

Start / End Page

191 / 198

Related Subject Headings

  • Pyrethrins
  • Neurotoxins
  • Genes, Recessive
  • Drug Resistance, Multiple
  • DDT
  • Cockroaches
  • Biochemistry & Molecular Biology
  • Animals
  • 3109 Zoology
  • 3101 Biochemistry and cell biology