An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.
Publication
, Journal Article
Huang, L; Jones, AME; Searle, I; Patel, K; Vogler, H; Hubner, NC; Baulcombe, DC
Published in: Nature structural & molecular biology
January 2009
Genetic evidence indicates that plant-specific homologs of DNA-dependent RNA polymerase (Pol) II large subunits form Pol IV and Pol V complexes involved in small interfering RNA production and RNA-directed DNA methylation. Here we describe evidence that Pol V contains subunits shared with Pol II, but that RNA polymerase II subunit (RPB)-4 is missing from Pol V and that RPB5 is present as a Pol V-specific isomer, RPB5b. Pol V also has other proteins that are not present in Pol II, consistent with a role of this complex as an effector of silencing.
Duke Scholars
Published In
Nature structural & molecular biology
DOI
EISSN
1545-9985
ISSN
1545-9993
Publication Date
January 2009
Volume
16
Issue
1
Start / End Page
91 / 93
Related Subject Headings
- RNA, Small Interfering
- RNA Polymerase II
- RNA Interference
- Protein Subunits
- Phenotype
- Developmental Biology
- DNA-Directed RNA Polymerases
- DNA-Binding Proteins
- DNA Polymerase beta
- DNA
Citation
APA
Chicago
ICMJE
MLA
NLM
Huang, L., Jones, A. M. E., Searle, I., Patel, K., Vogler, H., Hubner, N. C., & Baulcombe, D. C. (2009). An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature Structural & Molecular Biology, 16(1), 91–93. https://doi.org/10.1038/nsmb.1539
Huang, Linfeng, Alexandra M. E. Jones, Iain Searle, Kanu Patel, Hannes Vogler, Nina C. Hubner, and David C. Baulcombe. “An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.” Nature Structural & Molecular Biology 16, no. 1 (January 2009): 91–93. https://doi.org/10.1038/nsmb.1539.
Huang L, Jones AME, Searle I, Patel K, Vogler H, Hubner NC, et al. An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature structural & molecular biology. 2009 Jan;16(1):91–3.
Huang, Linfeng, et al. “An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.” Nature Structural & Molecular Biology, vol. 16, no. 1, Jan. 2009, pp. 91–93. Epmc, doi:10.1038/nsmb.1539.
Huang L, Jones AME, Searle I, Patel K, Vogler H, Hubner NC, Baulcombe DC. An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature structural & molecular biology. 2009 Jan;16(1):91–93.
Published In
Nature structural & molecular biology
DOI
EISSN
1545-9985
ISSN
1545-9993
Publication Date
January 2009
Volume
16
Issue
1
Start / End Page
91 / 93
Related Subject Headings
- RNA, Small Interfering
- RNA Polymerase II
- RNA Interference
- Protein Subunits
- Phenotype
- Developmental Biology
- DNA-Directed RNA Polymerases
- DNA-Binding Proteins
- DNA Polymerase beta
- DNA