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The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy.

Publication ,  Journal Article
Ho, DS; Scialabba, D; Terry, RS; Ma, X; Chen, J; Sankin, GN; Xiang, G; Qi, R; Preminger, GM; Lipkin, ME; Zhong, P
Published in: J Endourol
June 2021

Purpose: Although cavitation during laser lithotripsy (LL) contributes to the Moses effect, the impact of cavitation on stone damage is less clear. Using different laser settings, we investigate the role of cavitation bubbles in energy delivery and stone damage. Materials and Methods: The role of cavitation in laser energy delivery was characterized by using photodetector measurements synced with high-speed imaging for laser pulses of varying durations. BegoStone samples were treated with the laser fiber oriented perpendicularly in contact with the stone in water or in air to assess the impact of cavitation on crater formation. Crater volume and geometry were quantified by using optical coherence tomography. Further, the role of cavitation in stone damage was elucidated by treatment in water with the fiber oriented parallel to the stone surface and by photoelastic imaging. Results: Longer pulse durations resulted in higher energy delivery but smaller craters. Stones treated in water resulted in greater volume, wider yet shallower craters compared with those treated in air. Stones treated with the parallel fiber showed crater formation after 15 pulses, confirmed by high-speed imaging of the bubble collapse with the resultant stress field captured by photoelastic imaging. Conclusions: Despite improved energy delivery, the longer pulse mode produced smaller crater volume, suggesting additional processes secondary to photothermal ablation are involved in stone damage. Our critical observations of the difference in stone damage treated in water vs in air, combined with the crater formation by parallel fiber, suggest that cavitation is a contributor to stone damage during LL.

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Published In

J Endourol

DOI

EISSN

1557-900X

Publication Date

June 2021

Volume

35

Issue

6

Start / End Page

860 / 870

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Lithotripsy, Laser
  • Lithotripsy
  • Kidney Calculi
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Ho, D. S., Scialabba, D., Terry, R. S., Ma, X., Chen, J., Sankin, G. N., … Zhong, P. (2021). The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy. J Endourol, 35(6), 860–870. https://doi.org/10.1089/end.2020.0349
Ho, Derek S., Dominick Scialabba, Russell S. Terry, Xiaojian Ma, Junqin Chen, Georgy N. Sankin, Gaoming Xiang, et al. “The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy.J Endourol 35, no. 6 (June 2021): 860–70. https://doi.org/10.1089/end.2020.0349.
Ho DS, Scialabba D, Terry RS, Ma X, Chen J, Sankin GN, et al. The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy. J Endourol. 2021 Jun;35(6):860–70.
Ho, Derek S., et al. “The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy.J Endourol, vol. 35, no. 6, June 2021, pp. 860–70. Pubmed, doi:10.1089/end.2020.0349.
Ho DS, Scialabba D, Terry RS, Ma X, Chen J, Sankin GN, Xiang G, Qi R, Preminger GM, Lipkin ME, Zhong P. The Role of Cavitation in Energy Delivery and Stone Damage During Laser Lithotripsy. J Endourol. 2021 Jun;35(6):860–870.
Journal cover image

Published In

J Endourol

DOI

EISSN

1557-900X

Publication Date

June 2021

Volume

35

Issue

6

Start / End Page

860 / 870

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Lithotripsy, Laser
  • Lithotripsy
  • Kidney Calculi
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences