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Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014).

Publication ,  Journal Article
Graves, WC; Oyesanya, TO; Gormley, M; Røe, C; Andelic, N; Seel, RT; Lu, J
Published in: Brain injury
February 2021

Objectives: This study aimed to: (1) evaluate pre- and in-hospital mortality for moderate-to-severe TBI in the U.S. by injury type (blunt vs. penetrating) and (2) estimate annual regression-adjusted mortality from 2008-2014.Methods: Data were analyzed from the National Trauma Data Bank (N=247,648). Multivariable logistic regression analyses were performed by injury type to assess changes in mortality between study periods (early period: 2008-2010; late period: 2011-2014) and to estimate annual regression-adjusted mortality. Mortality odds ratios and 95% confidence intervals were calculated.Results: Total observed mortality was 18.8%. After covariate adjustment, patients in the late period had an increased odds of prehospital mortality compared to patients in the early period for blunt (OR: 4.69; 95%CI: 4.41-4.98) and penetrating trauma (OR: 4.71; 95%CI: 4.39-5.06). In contrast, patients in the late period had a decreased odds of in-hospital mortality compared to patients in the early period for blunt (OR: 0.95; 95%CI: 0.91-0.98) and penetrating trauma (OR: 0.92; 95%CI: 0.85-0.98).Conclusions: The decreasing in-hospital mortality trend is consistent with previous literature. Additional research is warranted to validate the observed increase in prehospital mortality and to identify best practices that can improve prehospital outcomes for patients with moderate-to-severe TBI.

Duke Scholars

Published In

Brain injury

DOI

EISSN

1362-301X

ISSN

0269-9052

Publication Date

February 2021

Volume

35

Issue

3

Start / End Page

265 / 274

Related Subject Headings

  • Wounds, Penetrating
  • Retrospective Studies
  • Rehabilitation
  • Odds Ratio
  • Injury Severity Score
  • Humans
  • Hospital Mortality
  • Databases, Factual
  • Brain Injuries, Traumatic
  • 5203 Clinical and health psychology
 

Citation

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Chicago
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MLA
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Graves, W. C., Oyesanya, T. O., Gormley, M., Røe, C., Andelic, N., Seel, R. T., & Lu, J. (2021). Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014). Brain Injury, 35(3), 265–274. https://doi.org/10.1080/02699052.2021.1873419
Graves, Whitney C., Tolu O. Oyesanya, Mirinda Gormley, Cecilie Røe, Nada Andelic, Ronald T. Seel, and Juan Lu. “Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014).Brain Injury 35, no. 3 (February 2021): 265–74. https://doi.org/10.1080/02699052.2021.1873419.
Graves WC, Oyesanya TO, Gormley M, Røe C, Andelic N, Seel RT, et al. Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014). Brain injury. 2021 Feb;35(3):265–74.
Graves, Whitney C., et al. “Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014).Brain Injury, vol. 35, no. 3, Feb. 2021, pp. 265–74. Epmc, doi:10.1080/02699052.2021.1873419.
Graves WC, Oyesanya TO, Gormley M, Røe C, Andelic N, Seel RT, Lu J. Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014). Brain injury. 2021 Feb;35(3):265–274.

Published In

Brain injury

DOI

EISSN

1362-301X

ISSN

0269-9052

Publication Date

February 2021

Volume

35

Issue

3

Start / End Page

265 / 274

Related Subject Headings

  • Wounds, Penetrating
  • Retrospective Studies
  • Rehabilitation
  • Odds Ratio
  • Injury Severity Score
  • Humans
  • Hospital Mortality
  • Databases, Factual
  • Brain Injuries, Traumatic
  • 5203 Clinical and health psychology