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Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography.

Publication ,  Journal Article
Cai, S; Therattil, A; Vajzovic, L
Published in: Dev Ophthalmol
2021

Intraoperative portable handheld and microscope-integrated OCT enhance the pediatric vitreoretinal surgeon's diagnostic abilities during examination under anesthesia and surgery, particularly in children who are challenging to examine preoperatively due to young age or ocular trauma. Improved OCT-guided visualization of vitreoretinal anatomic relationships has the potential to improve surgical safety and efficiency. In retinopathy of prematurity and other pediatric retinal vascular conditions, intraoperative OCT can be critical for distinguishing between retinoschisis and retinal detachment and highlighting abnormalities of the vitreoretinal interface that may contribute to development of tractional retinal detachments. During retinal detachment repair, intraoperative OCT aids identification of subtle retinal breaks, residual subretinal fluid, retained perfluorocarbon, preretinal membranes, and residual hyaloid, among other findings. In macular surgery, intraoperative OCT has demonstrated value in confirming completion or lack thereof of epiretinal and internal limiting membrane peeling and differentiating between lamellar and full-thickness macular holes. OCT-guided subretinal bleb formation and genetic vector delivery are critical to ensuring accurate localization of subretinal gene delivery for inherited retinal degenerations. Research on development of OCT-compatible surgical instruments, real-time three-dimensional volumetric OCT imaging, and integration with intraoperative OCT angiography are anticipated to further increase the utility of intraoperative OCT in pediatric vitreoretinal surgical decision-making.

Duke Scholars

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Published In

Dev Ophthalmol

DOI

EISSN

1662-2790

Publication Date

2021

Volume

61

Start / End Page

15 / 25

Location

Switzerland

Related Subject Headings

  • Vitreoretinal Surgery
  • Tomography, Optical Coherence
  • Surgery, Computer-Assisted
  • Retinal Diseases
  • Retina
  • Ophthalmology & Optometry
  • Humans
  • Child
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cai, S., Therattil, A., & Vajzovic, L. (2021). Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography. Dev Ophthalmol, 61, 15–25. https://doi.org/10.1159/000511818
Cai, Sophie, Anthony Therattil, and Lejla Vajzovic. “Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography.Dev Ophthalmol 61 (2021): 15–25. https://doi.org/10.1159/000511818.
Cai S, Therattil A, Vajzovic L. Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography. Dev Ophthalmol. 2021;61:15–25.
Cai, Sophie, et al. “Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography.Dev Ophthalmol, vol. 61, 2021, pp. 15–25. Pubmed, doi:10.1159/000511818.
Cai S, Therattil A, Vajzovic L. Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography. Dev Ophthalmol. 2021;61:15–25.
Journal cover image

Published In

Dev Ophthalmol

DOI

EISSN

1662-2790

Publication Date

2021

Volume

61

Start / End Page

15 / 25

Location

Switzerland

Related Subject Headings

  • Vitreoretinal Surgery
  • Tomography, Optical Coherence
  • Surgery, Computer-Assisted
  • Retinal Diseases
  • Retina
  • Ophthalmology & Optometry
  • Humans
  • Child