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Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.

Publication ,  Chapter
Allen, TA; Cheng, K
January 2021

Cancer mortality rates are primarily a result of cancer metastasis. Recent advances in microscopy technology allow for the imaging of circulating tumor cells (CTCs) as they extravasate (exit) blood vessels, a key step in the metastasis process. Here, we describe the use of intravital microscopy techniques to image and isolate both extravasating melanoma CTCs and the extravasation-participating endothelial cells. These techniques can be used as a means to study cancer metastasis and as a screening tool for anticancer therapeutics.

Duke Scholars

DOI

Publication Date

January 2021

Volume

2265

Start / End Page

417 / 425

Related Subject Headings

  • Zebrafish
  • Neoplastic Cells, Circulating
  • Neoplasm Metastasis
  • Melanoma, Experimental
  • Intravital Microscopy
  • Endothelial Cells
  • Developmental Biology
  • Cell Line, Tumor
  • Animals, Genetically Modified
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Allen, T. A., & Cheng, K. (2021). Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis. (Vol. 2265, pp. 417–425). https://doi.org/10.1007/978-1-0716-1205-7_30
Allen, Tyler A., and Ke Cheng. “Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.,” 2265:417–25, 2021. https://doi.org/10.1007/978-1-0716-1205-7_30.
Allen, Tyler A., and Ke Cheng. Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis. Vol. 2265, 2021, pp. 417–25. Epmc, doi:10.1007/978-1-0716-1205-7_30.

DOI

Publication Date

January 2021

Volume

2265

Start / End Page

417 / 425

Related Subject Headings

  • Zebrafish
  • Neoplastic Cells, Circulating
  • Neoplasm Metastasis
  • Melanoma, Experimental
  • Intravital Microscopy
  • Endothelial Cells
  • Developmental Biology
  • Cell Line, Tumor
  • Animals, Genetically Modified
  • Animals