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Left lateral segment liver volume is not correlated with anthropometric measures.

Publication ,  Journal Article
Shaw, BI; Schwartz, FR; Samoylova, ML; Barbas, AS; McElroy, LM; Berg, C; Sudan, DL; Marin, D; Ravindra, KV
Published in: HPB (Oxford)
December 2021

BACKGROUND: Liver transplantation is definitive therapy for end stage liver disease in pediatric patients. Living donor liver transplantation (LDLT) with the left lateral segment (LLS) is often a feasible option. However, the size of LLS is an important factor in donor suitability - particularly when the recipient weighs less than 10 kg. In the present study, we sought to define a formula for estimating left lateral segment volume (LLSV) in potential LLS donors. METHODS: We obtained demographic and anthropometric measurements on 50 patients with Computed Tomography (CT) scans to determine whole liver volume (WLV), right liver volume (RLV), and LLSV. We performed univariable and multivariable linear regression with backwards stepwise variable selection (p < 0.10) to determine final models. RESULTS: Our study found that previously reported anthropometric and demographics variables correlated with volume were significantly associated with WLV and RLV. On univariable analysis, no demographic or anthropometric measures were correlated with LLSV. On multivariable analysis, LLSV was poorly predicted by the final model (R2 = 0.10, Coefficient of Variation [CV] = 42.2) relative to WLV (R2 = 0.33, CV = 18.8) and RLV (R2 = 0.41, CV = 15.8). CONCLUSION: Potential LLS living donors should not be excluded based on anthropometric data: all potential donors should be evaluated regardless of their size.

Duke Scholars

Published In

HPB (Oxford)

DOI

EISSN

1477-2574

Publication Date

December 2021

Volume

23

Issue

12

Start / End Page

1830 / 1836

Location

England

Related Subject Headings

  • Surgery
  • Living Donors
  • Liver Transplantation
  • Liver
  • Humans
  • End Stage Liver Disease
  • Child
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Shaw, B. I., Schwartz, F. R., Samoylova, M. L., Barbas, A. S., McElroy, L. M., Berg, C., … Ravindra, K. V. (2021). Left lateral segment liver volume is not correlated with anthropometric measures. HPB (Oxford), 23(12), 1830–1836. https://doi.org/10.1016/j.hpb.2021.04.018
Shaw, Brian I., Fides R. Schwartz, Mariya L. Samoylova, Andrew S. Barbas, Lisa M. McElroy, Carl Berg, Debra L. Sudan, Daniele Marin, and Kadiyala V. Ravindra. “Left lateral segment liver volume is not correlated with anthropometric measures.HPB (Oxford) 23, no. 12 (December 2021): 1830–36. https://doi.org/10.1016/j.hpb.2021.04.018.
Shaw BI, Schwartz FR, Samoylova ML, Barbas AS, McElroy LM, Berg C, et al. Left lateral segment liver volume is not correlated with anthropometric measures. HPB (Oxford). 2021 Dec;23(12):1830–6.
Shaw, Brian I., et al. “Left lateral segment liver volume is not correlated with anthropometric measures.HPB (Oxford), vol. 23, no. 12, Dec. 2021, pp. 1830–36. Pubmed, doi:10.1016/j.hpb.2021.04.018.
Shaw BI, Schwartz FR, Samoylova ML, Barbas AS, McElroy LM, Berg C, Sudan DL, Marin D, Ravindra KV. Left lateral segment liver volume is not correlated with anthropometric measures. HPB (Oxford). 2021 Dec;23(12):1830–1836.
Journal cover image

Published In

HPB (Oxford)

DOI

EISSN

1477-2574

Publication Date

December 2021

Volume

23

Issue

12

Start / End Page

1830 / 1836

Location

England

Related Subject Headings

  • Surgery
  • Living Donors
  • Liver Transplantation
  • Liver
  • Humans
  • End Stage Liver Disease
  • Child
  • 3202 Clinical sciences
  • 1103 Clinical Sciences