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Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals.

Publication ,  Journal Article
Stagg, B; Mariottoni, EB; Berchuck, S; Jammal, A; Elam, AR; Hess, R; Kawamoto, K; Haaland, B; Medeiros, FA
Published in: Br J Ophthalmol
August 2022

BACKGROUND/AIMS: To investigate racial differences in the variability of longitudinal visual field testing in a 'real-world' clinical population, evaluate how these differences are influenced by socioeconomic status, and estimate the impact of differences in variability on the time to detect visual field progression. METHODS: This retrospective observational cohort study used data from 1103 eyes from 751 White individuals and 428 eyes from 317 black individuals. Linear regression was performed on the standard automated perimetry mean deviation values for each eye over time. The SD of the residuals from the trend lines was calculated and used as a measure of variability for each eye. The association of race with the SD of the residuals was evaluated using a multivariable generalised estimating equation model with an interaction between race and zip code income. Computer simulations were used to estimate the time to detect visual field progression in the two racial groups. RESULTS: Black patients had larger visual field variability over time compared with white patients, even when adjusting for zip code level socioeconomic variables (SD of residuals for Black patients=1.53 dB (95% CI 1.43 to 1.64); for white patients=1.26 dB (95% CI 1.14 to 1.22); mean difference: 0.28 (95% CI 0.15 to 0.41); p<0.001). The difference in visual field variability between black and white patients was greater at lower levels of income and led to a delay in detection of glaucoma progression. CONCLUSION: Black patients had larger visual field variability compared with white patients. This relationship was strongly influenced by socioeconomic status and may partially explain racial disparities in glaucoma outcomes.

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Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

August 2022

Volume

106

Issue

8

Start / End Page

1115 / 1120

Location

England

Related Subject Headings

  • Visual Fields
  • Visual Field Tests
  • Vision Disorders
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Intraocular Pressure
  • Humans
  • Glaucoma
  • Follow-Up Studies
  • Disease Progression
 

Citation

APA
Chicago
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MLA
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Stagg, B., Mariottoni, E. B., Berchuck, S., Jammal, A., Elam, A. R., Hess, R., … Medeiros, F. A. (2022). Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals. Br J Ophthalmol, 106(8), 1115–1120. https://doi.org/10.1136/bjophthalmol-2020-318104
Stagg, Brian, Eduardo B. Mariottoni, Samuel Berchuck, Alessandro Jammal, Angela R. Elam, Rachel Hess, Kensaku Kawamoto, Benjamin Haaland, and Felipe A. Medeiros. “Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals.Br J Ophthalmol 106, no. 8 (August 2022): 1115–20. https://doi.org/10.1136/bjophthalmol-2020-318104.
Stagg B, Mariottoni EB, Berchuck S, Jammal A, Elam AR, Hess R, et al. Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals. Br J Ophthalmol. 2022 Aug;106(8):1115–20.
Stagg, Brian, et al. “Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals.Br J Ophthalmol, vol. 106, no. 8, Aug. 2022, pp. 1115–20. Pubmed, doi:10.1136/bjophthalmol-2020-318104.
Stagg B, Mariottoni EB, Berchuck S, Jammal A, Elam AR, Hess R, Kawamoto K, Haaland B, Medeiros FA. Longitudinal visual field variability and the ability to detect glaucoma progression in black and white individuals. Br J Ophthalmol. 2022 Aug;106(8):1115–1120.

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

August 2022

Volume

106

Issue

8

Start / End Page

1115 / 1120

Location

England

Related Subject Headings

  • Visual Fields
  • Visual Field Tests
  • Vision Disorders
  • Retrospective Studies
  • Ophthalmology & Optometry
  • Intraocular Pressure
  • Humans
  • Glaucoma
  • Follow-Up Studies
  • Disease Progression