Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire.

Publication ,  Journal Article
Vanga-Bosson, HA; Coffie, PA; Kanhon, S; Sloan, C; Kouakou, F; Eholie, SP; Kone, M; Dabis, F; Menan, H; Ekouevi, DK
Published in: Malar J
April 29, 2011

BACKGROUND: The World Health Organization (WHO) recommends using insecticide-treated mosquito nets (ITNs) and intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) to prevent malaria in sub-Saharan Africa. Data on IPT-SP coverage and factors associated with placental malaria parasitaemia and low birth weight (LBW) are scarce in Côte d'Ivoire. METHODS: A multicentre, cross-sectional survey was conducted in Côte d'Ivoire from March to September 2008 at six urban and semi-urban antenatal clinics. Standardized forms were used to collect the demographic information and medical histories of women and their offspring. IPT-SP coverage (≥2 doses) as well as placental and congenital malaria prevalence parasitaemia were estimated. Regression logistics were used to study factors associated with placental malaria and LBW (birth weight of alive babies < 2,500 grams). RESULTS: Overall, 2,044 women with a median age of 24 years were included in this study. Among them 1017 (49.8%) received ≥2 doses of IPT-SP and 694 (34.0%) received one dose. A total of 99 mothers (4.8%) had placental malaria, and of them, four cases of congenital malaria were diagnosed. Factors that protected from maternal placental malaria parasitaemia were the use of one dose (adjusted odds ratio (aOR), 0.32; 95%CI: 0.19-0.55) or ≥2 doses IPT-SP (aOR: 0.18; 95%CI: 0.10-0.32); the use of ITNs (aOR: 0.47; 95%CI: 0.27-0.82). LBW was associated with primigravidity and placental malaria parasitaemia. CONCLUSION: IPT-SP decreases the rate of placental malaria parasitaemia and has a strong dose effect. Despite relatively successful IPT-SP coverage in Côte d'Ivoire, substantial commitments from national authorities are urgently required for such public health campaigns. Strategies, such as providing IPT-SP free of charge and directly observing treatment, should be implemented to increase the use of IPT-SP as well as other prophylactic methods.

Duke Scholars

Published In

Malar J

DOI

EISSN

1475-2875

Publication Date

April 29, 2011

Volume

10

Start / End Page

105

Location

England

Related Subject Headings

  • Young Adult
  • Tropical Medicine
  • Sulfadoxine
  • Pyrimethamine
  • Pregnant Women
  • Pregnancy Complications
  • Pregnancy
  • Parasitemia
  • Malaria
  • Infant, Newborn
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vanga-Bosson, H. A., Coffie, P. A., Kanhon, S., Sloan, C., Kouakou, F., Eholie, S. P., … Ekouevi, D. K. (2011). Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. Malar J, 10, 105. https://doi.org/10.1186/1475-2875-10-105
Vanga-Bosson, Henriette A., Patrick A. Coffie, Serge Kanhon, Caroline Sloan, Firmin Kouakou, Serge P. Eholie, Moussa Kone, François Dabis, Hervé Menan, and Didier K. Ekouevi. “Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire.Malar J 10 (April 29, 2011): 105. https://doi.org/10.1186/1475-2875-10-105.
Vanga-Bosson HA, Coffie PA, Kanhon S, Sloan C, Kouakou F, Eholie SP, et al. Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. Malar J. 2011 Apr 29;10:105.
Vanga-Bosson, Henriette A., et al. “Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire.Malar J, vol. 10, Apr. 2011, p. 105. Pubmed, doi:10.1186/1475-2875-10-105.
Vanga-Bosson HA, Coffie PA, Kanhon S, Sloan C, Kouakou F, Eholie SP, Kone M, Dabis F, Menan H, Ekouevi DK. Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. Malar J. 2011 Apr 29;10:105.
Journal cover image

Published In

Malar J

DOI

EISSN

1475-2875

Publication Date

April 29, 2011

Volume

10

Start / End Page

105

Location

England

Related Subject Headings

  • Young Adult
  • Tropical Medicine
  • Sulfadoxine
  • Pyrimethamine
  • Pregnant Women
  • Pregnancy Complications
  • Pregnancy
  • Parasitemia
  • Malaria
  • Infant, Newborn