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Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): What We Know and Don't Know.

Publication ,  Journal Article
Arepally, GM; Ortel, TL
Published in: Blood
June 1, 2021

Development of vaccines to fight COVID19 has been a remarkable medical achievement. However, this global immunization effort has been complicated by a rare vaccine-related outcome characterized by thrombocytopenia and thrombosis in association with platelet-activating anti-platelet factor 4 antibodies. In this Spotlight article, we will discuss the recently described complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) occurring in response to certain COVID19 vaccines. Although information about this clinical condition is rapidly evolving, we will summarize our current understanding of VITT.

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Published In

Blood

DOI

EISSN

1528-0020

Publication Date

June 1, 2021

Location

United States

Related Subject Headings

  • Immunology
  • 3213 Paediatrics
  • 3201 Cardiovascular medicine and haematology
  • 3101 Biochemistry and cell biology
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Arepally, G. M., & Ortel, T. L. (2021). Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): What We Know and Don't Know. Blood. https://doi.org/10.1182/blood.2021012152
Arepally, Gowthami M., and Thomas L. Ortel. “Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): What We Know and Don't Know.Blood, June 1, 2021. https://doi.org/10.1182/blood.2021012152.
Arepally, Gowthami M., and Thomas L. Ortel. “Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): What We Know and Don't Know.Blood, June 2021. Pubmed, doi:10.1182/blood.2021012152.

Published In

Blood

DOI

EISSN

1528-0020

Publication Date

June 1, 2021

Location

United States

Related Subject Headings

  • Immunology
  • 3213 Paediatrics
  • 3201 Cardiovascular medicine and haematology
  • 3101 Biochemistry and cell biology
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology