Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'.

Publication ,  Journal Article
Stöck, M; Kratochvíl, L; Kuhl, H; Rovatsos, M; Evans, BJ; Suh, A; Valenzuela, N; Veyrunes, F; Zhou, Q; Gamble, T; Capel, B; Schartl, M; Guiguen, Y
Published in: Philos Trans R Soc Lond B Biol Sci
August 30, 2021

Triggers and biological processes controlling male or female gonadal differentiation vary in vertebrates, with sex determination (SD) governed by environmental factors or simple to complex genetic mechanisms that evolved repeatedly and independently in various groups. Here, we review sex evolution across major clades of vertebrates with information on SD, sexual development and reproductive modes. We offer an up-to-date review of divergence times, species diversity, genomic resources, genome size, occurrence and nature of polyploids, SD systems, sex chromosomes, SD genes, dosage compensation and sex-biased gene expression. Advances in sequencing technologies now enable us to study the evolution of SD at broader evolutionary scales, and we now hope to pursue a sexomics integrative research initiative across vertebrates. The vertebrate sexome comprises interdisciplinary and integrated information on sexual differentiation, development and reproduction at all biological levels, from genomes, transcriptomes and proteomes, to the organs involved in sexual and sex-specific processes, including gonads, secondary sex organs and those with transcriptional sex-bias. The sexome also includes ontogenetic and behavioural aspects of sexual differentiation, including malfunction and impairment of SD, sexual differentiation and fertility. Starting from data generated by high-throughput approaches, we encourage others to contribute expertise to building understanding of the sexomes of many key vertebrate species. This article is part of the theme issue 'Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part I)'.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Philos Trans R Soc Lond B Biol Sci

DOI

EISSN

1471-2970

Publication Date

August 30, 2021

Volume

376

Issue

1832

Start / End Page

20200426

Location

England

Related Subject Headings

  • Vertebrates
  • Testis
  • Sex Differentiation
  • Sex Determination Processes
  • Sex Chromosomes
  • Ovary
  • Male
  • Genome Size
  • Female
  • Evolutionary Biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Stöck, M., Kratochvíl, L., Kuhl, H., Rovatsos, M., Evans, B. J., Suh, A., … Guiguen, Y. (2021). A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'. Philos Trans R Soc Lond B Biol Sci, 376(1832), 20200426. https://doi.org/10.1098/rstb.2020.0426
Stöck, Matthias, Lukáš Kratochvíl, Heiner Kuhl, Michail Rovatsos, Ben J. Evans, Alexander Suh, Nicole Valenzuela, et al. “A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'.Philos Trans R Soc Lond B Biol Sci 376, no. 1832 (August 30, 2021): 20200426. https://doi.org/10.1098/rstb.2020.0426.
Stöck M, Kratochvíl L, Kuhl H, Rovatsos M, Evans BJ, Suh A, et al. A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'. Philos Trans R Soc Lond B Biol Sci. 2021 Aug 30;376(1832):20200426.
Stöck, Matthias, et al. “A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'.Philos Trans R Soc Lond B Biol Sci, vol. 376, no. 1832, Aug. 2021, p. 20200426. Pubmed, doi:10.1098/rstb.2020.0426.
Stöck M, Kratochvíl L, Kuhl H, Rovatsos M, Evans BJ, Suh A, Valenzuela N, Veyrunes F, Zhou Q, Gamble T, Capel B, Schartl M, Guiguen Y. A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'. Philos Trans R Soc Lond B Biol Sci. 2021 Aug 30;376(1832):20200426.
Journal cover image

Published In

Philos Trans R Soc Lond B Biol Sci

DOI

EISSN

1471-2970

Publication Date

August 30, 2021

Volume

376

Issue

1832

Start / End Page

20200426

Location

England

Related Subject Headings

  • Vertebrates
  • Testis
  • Sex Differentiation
  • Sex Determination Processes
  • Sex Chromosomes
  • Ovary
  • Male
  • Genome Size
  • Female
  • Evolutionary Biology