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Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review.

Publication ,  Journal Article
Turner, EL; Platt, AC; Gallis, JA; Tetreault, K; Easter, C; McKenzie, JE; Nash, S; Forbes, AB; Hemming, K; CRT Binary Outcome Reporting Group,
Published in: Lancet Glob Health
August 2021

Overstating the impact of interventions through incomplete or inaccurate reporting can lead to inappropriate scale-up of interventions with low impact. Accurate reporting of the impact of interventions is of great importance in global health research to protect scarce resources. In global health, the cluster randomised trial design is commonly used to evaluate complex, multicomponent interventions, and outcomes are often binary. Complete reporting of impact for binary outcomes means reporting both relative and absolute measures. We did a systematic review to assess reporting practices and potential to overstate impact in contemporary cluster randomised trials with binary primary outcome. We included all reports registered in the Cochrane Central Register of Controlled Trials of two-arm parallel cluster randomised trials with at least one binary primary outcome that were published in 2017. Of 73 cluster randomised trials, most (60 [82%]) showed incomplete reporting. Of 64 cluster randomised trials for which it was possible to evaluate, most (40 [63%]) reported results in such a way that impact could be overstated. Care is needed to report complete evidence of impact for the many interventions evaluated using the cluster randomised trial design worldwide.

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Published In

Lancet Glob Health

DOI

EISSN

2214-109X

Publication Date

August 2021

Volume

9

Issue

8

Start / End Page

e1163 / e1168

Location

England

Related Subject Headings

  • Risk
  • Research Design
  • Randomized Controlled Trials as Topic
  • Humans
  • Cluster Analysis
  • 4206 Public health
  • 4203 Health services and systems
  • 4202 Epidemiology
  • 1117 Public Health and Health Services
  • 0605 Microbiology
 

Citation

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Turner, E. L., Platt, A. C., Gallis, J. A., Tetreault, K., Easter, C., McKenzie, J. E., … CRT Binary Outcome Reporting Group, . (2021). Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review. Lancet Glob Health, 9(8), e1163–e1168. https://doi.org/10.1016/S2214-109X(21)00200-X
Turner, Elizabeth L., Alyssa C. Platt, John A. Gallis, Kaitlin Tetreault, Christina Easter, Joanne E. McKenzie, Stephen Nash, Andrew B. Forbes, Karla Hemming, and Karla CRT Binary Outcome Reporting Group. “Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review.Lancet Glob Health 9, no. 8 (August 2021): e1163–68. https://doi.org/10.1016/S2214-109X(21)00200-X.
Turner EL, Platt AC, Gallis JA, Tetreault K, Easter C, McKenzie JE, et al. Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review. Lancet Glob Health. 2021 Aug;9(8):e1163–8.
Turner, Elizabeth L., et al. “Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review.Lancet Glob Health, vol. 9, no. 8, Aug. 2021, pp. e1163–68. Pubmed, doi:10.1016/S2214-109X(21)00200-X.
Turner EL, Platt AC, Gallis JA, Tetreault K, Easter C, McKenzie JE, Nash S, Forbes AB, Hemming K, CRT Binary Outcome Reporting Group. Completeness of reporting and risks of overstating impact in cluster randomised trials: a systematic review. Lancet Glob Health. 2021 Aug;9(8):e1163–e1168.
Journal cover image

Published In

Lancet Glob Health

DOI

EISSN

2214-109X

Publication Date

August 2021

Volume

9

Issue

8

Start / End Page

e1163 / e1168

Location

England

Related Subject Headings

  • Risk
  • Research Design
  • Randomized Controlled Trials as Topic
  • Humans
  • Cluster Analysis
  • 4206 Public health
  • 4203 Health services and systems
  • 4202 Epidemiology
  • 1117 Public Health and Health Services
  • 0605 Microbiology