Towards living guidelines on cardiorenal outcomes in diabetes: A pilot project of the Taskforce of the Guideline Workshop 2020.
In June 2020, the Taskforce of the Guideline Workshop 2019 convened via teleconferencing to initiate a pilot project that demonstrates the various processes and considerations involved in developing high-quality, evidence-based clinical practice guidelines for the medical management of individuals with type 2 diabetes (T2D) and its associated comorbidities, including cardiovascular disease (CVD) and chronic kidney disease (CKD). The goal of the pilot project was to create evidence-based guidelines for use of sodium-glucose transport protein 2 inhibitors (SGLT2-I) when managing very high risk T2D patients, evidenced by the presence of both CVD and CKD. For this purpose the Taskforce represented a guideline panel and made use of synthesized evidence from an ongoing BMJ Rapid Recommendations project on SGLT2-I and GLP-1 receptor agonists. Results from the Taskforce pilot project demonstrated the value, feasibility and utility of using a step-wise approach to identifying and grading evidence and then developing actionable recommendations for utilizing SGLT2-I in this at-risk T2D population. This report describes the various steps involved in the process and explains how it can be utilized to rapidly develop recommendations in a format that is easy to use and can be quickly updated as new evidence becomes available, also within the emerging concept of living guidelines.
Duke Scholars
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Related Subject Headings
- Sodium-Glucose Transporter 2 Inhibitors
- Sodium-Glucose Transport Proteins
- Practice Guidelines as Topic
- Pilot Projects
- Hypoglycemic Agents
- Humans
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- Cardiovascular Diseases
- 5203 Clinical and health psychology
Citation
Published In
DOI
EISSN
Publication Date
Volume
Start / End Page
Location
Related Subject Headings
- Sodium-Glucose Transporter 2 Inhibitors
- Sodium-Glucose Transport Proteins
- Practice Guidelines as Topic
- Pilot Projects
- Hypoglycemic Agents
- Humans
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- Cardiovascular Diseases
- 5203 Clinical and health psychology