Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.
Publication
, Journal Article
Arepally, GM; Ortel, TL
Published in: Blood
July 29, 2021
The development of vaccines to fight COVID-19 has been a remarkable medical achievement. However, this global immunization effort has been complicated by a rare vaccine-related outcome characterized by thrombocytopenia and thrombosis in association with platelet-activating anti-platelet factor 4 antibodies. In this Spotlight, we will discuss the recently described complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) occurring in response to certain COVID-19 vaccines. Although information about this clinical condition is rapidly evolving, we will summarize our current understanding of VITT.
Duke Scholars
Published In
Blood
DOI
EISSN
1528-0020
Publication Date
July 29, 2021
Volume
138
Issue
4
Start / End Page
293 / 298
Location
United States
Related Subject Headings
- SARS-CoV-2
- Purpura, Thrombocytopenic, Idiopathic
- Immunology
- Humans
- Heparin
- Disease Management
- COVID-19 Vaccines
- COVID-19
- Anticoagulants
- 3213 Paediatrics
Citation
APA
Chicago
ICMJE
MLA
NLM
Arepally, G. M., & Ortel, T. L. (2021). Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know. Blood, 138(4), 293–298. https://doi.org/10.1182/blood.2021012152
Arepally, Gowthami M., and Thomas L. Ortel. “Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.” Blood 138, no. 4 (July 29, 2021): 293–98. https://doi.org/10.1182/blood.2021012152.
Arepally GM, Ortel TL. Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know. Blood. 2021 Jul 29;138(4):293–8.
Arepally, Gowthami M., and Thomas L. Ortel. “Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.” Blood, vol. 138, no. 4, July 2021, pp. 293–98. Pubmed, doi:10.1182/blood.2021012152.
Arepally GM, Ortel TL. Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know. Blood. 2021 Jul 29;138(4):293–298.
Published In
Blood
DOI
EISSN
1528-0020
Publication Date
July 29, 2021
Volume
138
Issue
4
Start / End Page
293 / 298
Location
United States
Related Subject Headings
- SARS-CoV-2
- Purpura, Thrombocytopenic, Idiopathic
- Immunology
- Humans
- Heparin
- Disease Management
- COVID-19 Vaccines
- COVID-19
- Anticoagulants
- 3213 Paediatrics