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Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society.

Publication ,  Journal Article
Mitchell, JD; Cehic, DA; Morgia, M; Bergom, C; Toohey, J; Guerrero, PA; Ferencik, M; Kikuchi, R; Carver, JR; Zaha, VG; Alvarez-Cardona, JA ...
Published in: JACC CardioOncol
September 2021

Radiation therapy is a cornerstone of cancer therapy, with >50% of patients undergoing therapeutic radiation. As a result of widespread use and improved survival, there is increasing focus on the potential long-term effects of ionizing radiation, especially cardiovascular toxicity. Radiation therapy can lead to atherosclerosis of the vasculature as well as valvular, myocardial, and pericardial dysfunction. We present a consensus statement from the International Cardio-Oncology Society based on general principles of radiotherapy delivery and cardiovascular risk assessment and risk mitigation in this population. Anatomical-based recommendations for cardiovascular management and follow-up are provided, and a priority is given to the early detection of atherosclerotic vascular disease on imaging to help guide preventive therapy. Unique management considerations in radiation-induced cardiovascular disease are also discussed. Recommendations are based on the most current literature and represent a unanimous consensus by the multidisciplinary expert panel.

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Published In

JACC CardioOncol

DOI

EISSN

2666-0873

Publication Date

September 2021

Volume

3

Issue

3

Start / End Page

360 / 380

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
MLA
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Mitchell, J. D., Cehic, D. A., Morgia, M., Bergom, C., Toohey, J., Guerrero, P. A., … Dent, S. F. (2021). Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society. JACC CardioOncol, 3(3), 360–380. https://doi.org/10.1016/j.jaccao.2021.06.003
Mitchell, Joshua D., Daniel A. Cehic, Marita Morgia, Carmen Bergom, Joanne Toohey, Patricia A. Guerrero, Maros Ferencik, et al. “Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society.JACC CardioOncol 3, no. 3 (September 2021): 360–80. https://doi.org/10.1016/j.jaccao.2021.06.003.
Mitchell JD, Cehic DA, Morgia M, Bergom C, Toohey J, Guerrero PA, et al. Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society. JACC CardioOncol. 2021 Sep;3(3):360–80.
Mitchell, Joshua D., et al. “Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society.JACC CardioOncol, vol. 3, no. 3, Sept. 2021, pp. 360–80. Pubmed, doi:10.1016/j.jaccao.2021.06.003.
Mitchell JD, Cehic DA, Morgia M, Bergom C, Toohey J, Guerrero PA, Ferencik M, Kikuchi R, Carver JR, Zaha VG, Alvarez-Cardona JA, Szmit S, Daniele AJ, Lopez-Mattei J, Zhang L, Herrmann J, Nohria A, Lenihan DJ, Dent SF. Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society. JACC CardioOncol. 2021 Sep;3(3):360–380.
Journal cover image

Published In

JACC CardioOncol

DOI

EISSN

2666-0873

Publication Date

September 2021

Volume

3

Issue

3

Start / End Page

360 / 380

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 3201 Cardiovascular medicine and haematology