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Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial

Publication ,  Journal Article
Piotrowicz, E; Pencina, M; Opolski, G; Zaręba, W; Banach, M; Kowalik, I; Orzechowski, P; Główczyńska, R; Szalewska, D; Pluta, S; Kalarus, Z ...
Published in: Applied Sciences (Switzerland)
March 1, 2022

(1) Background Adherence to treatment guidelines in heart failure (HF) patients is of major prognostic importance, but thorough implementation of guidelines in routine care remains insufficient. Introducing hybrid comprehensive telerehabilitation (HCTR) consisting of telecare, telerehabilitation, and remote monitoring of implantable devices might be an option to improve adherence to recommendation and can affect the prognosis. The purpose is to investigate the association of adherence to HCTR with mortality and hospitalization. (2) Methods This analysis formed part of TELEREH-HF multi-center, randomized trial that enrolled 850HF patients (NYHA I-III;LVEF ≤ 40%). Patients were randomized 1:1 to 9-week HCTR (1 week in hospital and 8 weeks at home) plus usual care or usual care only and followed-up for 14 to 26 months. This analysis focuses on the HCTR group. Adherent patients were those who adhered both to the number of training sessions prescribed and to the duration of the prescribed cycle by at least 80%; non-adherent patients were those who adhered<20% to the prescribed number of training sessions and their duration. The remaining patients were classified as partially adherent. (3) Results There were 350 (88.4%) adherent patients, 39 (9.8%) partially adherent patients, and 7 (1.8%) non-adherent patients. There were 46 deaths during follow-up. Non-adherence or partial adherence was associated with higher risk of cardiovascular (CV) mortality (hazard ratio (HR) = 2.62, p = 0.021); all-cause mortality or HF hospitalization (HR = 1.71, p = 0.038); CV mortality or HF hospitalization (HR = 1.89, p = 0.014). (4) Conclusions The adherence to HCTR was high. Adherence to HCTR was associated with improved prognosis for CV mortality and the reduction in the combined outcome of CV mortality or HF hospitalization.

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Published In

Applied Sciences (Switzerland)

DOI

EISSN

2076-3417

Publication Date

March 1, 2022

Volume

12

Issue

5
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Piotrowicz, E., Pencina, M., Opolski, G., Zaręba, W., Banach, M., Kowalik, I., … Piotrowicz, R. (2022). Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial. Applied Sciences (Switzerland), 12(5). https://doi.org/10.3390/app12052595
Piotrowicz, E., M. Pencina, G. Opolski, W. Zaręba, M. Banach, I. Kowalik, P. Orzechowski, et al. “Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial.” Applied Sciences (Switzerland) 12, no. 5 (March 1, 2022). https://doi.org/10.3390/app12052595.
Piotrowicz E, Pencina M, Opolski G, Zaręba W, Banach M, Kowalik I, et al. Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial. Applied Sciences (Switzerland). 2022 Mar 1;12(5).
Piotrowicz, E., et al. “Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial.” Applied Sciences (Switzerland), vol. 12, no. 5, Mar. 2022. Scopus, doi:10.3390/app12052595.
Piotrowicz E, Pencina M, Opolski G, Zaręba W, Banach M, Kowalik I, Orzechowski P, Główczyńska R, Szalewska D, Pluta S, Kalarus Z, Irzmański R, Piotrowicz R. Heart Failure Patients’ Adherence to Hybrid Comprehensive Telerehabilitation and Its Impact on Prognosis Based on Data from TELEREH-HF Randomized Clinical Trial. Applied Sciences (Switzerland). 2022 Mar 1;12(5).

Published In

Applied Sciences (Switzerland)

DOI

EISSN

2076-3417

Publication Date

March 1, 2022

Volume

12

Issue

5