Skip to main content
Journal cover image

T cell metabolism in graft-versus-host disease.

Publication ,  Journal Article
Zou, Y; Chen, BJ
Published in: Blood Sci
January 2020

Graft-versus-host disease (GVHD) is a major source of morbidity and mortality following allogeneic hematopoietic stem cell transplant (allo-HSCT), one of the most effective approaches to treat hematopoietic malignancies.1 However, current prophylaxis regimens and treatments that reduce the detrimental effect of acute GVHD can be offset by increased incidence in opportunistic infections and relapse of the primary malignancy.2 In addition, the majority of the approaches that inhibit T cell responses are non-specific, resulting in the inhibition of both alloreactive T cells and protective T cells from the donor. Therefore, there is an increase in the demand to develop novel approaches that selectively target alloreactive T cells. One potential means to address this issue is to take advantage of the unique metabolic profile of activated T cells.

Duke Scholars

Published In

Blood Sci

DOI

EISSN

2543-6368

Publication Date

January 2020

Volume

2

Issue

1

Start / End Page

16 / 21

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zou, Y., & Chen, B. J. (2020). T cell metabolism in graft-versus-host disease. Blood Sci, 2(1), 16–21. https://doi.org/10.1097/BS9.0000000000000035
Zou, Yujing, and Benny J. Chen. “T cell metabolism in graft-versus-host disease.Blood Sci 2, no. 1 (January 2020): 16–21. https://doi.org/10.1097/BS9.0000000000000035.
Zou Y, Chen BJ. T cell metabolism in graft-versus-host disease. Blood Sci. 2020 Jan;2(1):16–21.
Zou, Yujing, and Benny J. Chen. “T cell metabolism in graft-versus-host disease.Blood Sci, vol. 2, no. 1, Jan. 2020, pp. 16–21. Pubmed, doi:10.1097/BS9.0000000000000035.
Zou Y, Chen BJ. T cell metabolism in graft-versus-host disease. Blood Sci. 2020 Jan;2(1):16–21.
Journal cover image

Published In

Blood Sci

DOI

EISSN

2543-6368

Publication Date

January 2020

Volume

2

Issue

1

Start / End Page

16 / 21

Location

United States