Current Appointments & Affiliations
Professor of Medicine
·
2021 - Present
Medicine, Hematologic Malignancies and Cellular Therapy,
Medicine
Member of the Duke Cancer Institute
·
1996 - Present
Duke Cancer Institute,
Institutes and Centers
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Imatinib-Sensitive Chronic Myeloid Leukaemia Is Associated with mtDNA Mutations and Reduced Oxphos Capacity
Conference Blood · November 5, 2024 Introduction: Therapy resistance driven by Leukemic Stem/Progenitor Cells (LSPCs) remains a challenge in Chronic Myeloid Leukemia (CML).Recent studies indicate that Tyrosine Kinase Inhibi ... Full text CiteNT-I7, a Long-Acting Interleukin-7 Molecule, Promotes T Cell Reconstitution Following Radiation Injury through Thymic-Dependent and Independent Pathways
Conference Blood · November 5, 2024 Total body irradiation (TBI) causes suppression of hematopoiesis and T cell depletion. T cell lymphopenia following radiation exposure increases the risk of opportunistic infections. Curr ... Full text CiteHuman Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury
Conference Blood · November 5, 2024 Endothelial cells (ECs) are the major participants in bone marrow microenvironment and key regulators of hematopoiesis. ECs regulate hematopoiesis at least in part by shedding the extrace ... Full text CiteEducation
Sun Yat Sen University (China) ·
1991
M.D.