bioRxiv
Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus
Preprints
Hoy, M; Park, E; Lee, H; Lim, WY; Cole, C; DeBouver, N; Bobay, B; Pierce, P; Fox, D; Ciofani, M; Juvvadi, P; Steinbach, W; Hong, J; Heitman, J
2022
Duke Scholars
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Hoy, M., Park, E., Lee, H., Lim, W. Y., Cole, C., DeBouver, N., … Heitman, J. (2022). Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus. bioRxiv. https://doi.org/10.1101/2022.03.25.485831
Hoy, Michael, Eunchong Park, Hyunji Lee, Won Young Lim, Christopher Cole, Nicholas DeBouver, Benjamin Bobay, et al. “Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus.” BioRxiv, 2022. https://doi.org/10.1101/2022.03.25.485831.
Hoy M, Park E, Lee H, Lim WY, Cole C, DeBouver N, et al. Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus. bioRxiv. 2022.
Hoy, Michael, et al. “Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus.” BioRxiv, 2022. Epmc, doi:10.1101/2022.03.25.485831.
Hoy M, Park E, Lee H, Lim WY, Cole C, DeBouver N, Bobay B, Pierce P, Fox D, Ciofani M, Juvvadi P, Steinbach W, Hong J, Heitman J. Structure-guided synthesis of FK506 and FK520 analogs with increased selectivity exhibit in vivo therapeutic efficacy against Cryptococcus. bioRxiv. 2022.