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Benefits from disease-burden reduction for type 2 diabetes and obesity through comprehensive regulatory restrictions on phthalate use in China

Publication ,  Journal Article
Shi, S; Zhang, J; Gong, J; Zhao, B
Published in: One Earth
April 15, 2022

Evidence is accumulating that the increasing incidence of type 2 diabetes and obesity is correlated with exposure to certain phthalates, which brings growing concern to the public health of China. However, the extent to which phthalate restrictions will alleviate these health concerns remains unclear. Here, we employed a sequential modeling approach to evaluate the impact that a series of restrictions would have on the mass of phthalates in the use phase, indoor concentrations, exposure, and the attributable disease burden of type 2 diabetes and obesity in adults. We show that, compared with the business-as-usual scenario, the implementation of the strongest restriction on the concerned phthalates in 2016 can decrease the use of phthalates by up to 91.2%, indoor airborne phthalate concentrations by 93.8%, and indoor dust-phase phthalate concentrations by 90.2% by 2031. Correspondingly, the decrease in phthalate exposure would result in a health benefit of 134.6 billion CNY. These findings call for the urgent need to restrict the use of certain phthalates to reduce the burden of type 2 diabetes and obesity in China.

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Published In

One Earth

DOI

EISSN

2590-3322

ISSN

2590-3330

Publication Date

April 15, 2022

Volume

5

Issue

4

Start / End Page

380 / 391

Related Subject Headings

  • 41 Environmental sciences
  • 37 Earth sciences
 

Citation

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Chicago
ICMJE
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Shi, S., Zhang, J., Gong, J., & Zhao, B. (2022). Benefits from disease-burden reduction for type 2 diabetes and obesity through comprehensive regulatory restrictions on phthalate use in China. One Earth, 5(4), 380–391. https://doi.org/10.1016/j.oneear.2022.03.013
Shi, S., J. Zhang, J. Gong, and B. Zhao. “Benefits from disease-burden reduction for type 2 diabetes and obesity through comprehensive regulatory restrictions on phthalate use in China.” One Earth 5, no. 4 (April 15, 2022): 380–91. https://doi.org/10.1016/j.oneear.2022.03.013.
Shi, S., et al. “Benefits from disease-burden reduction for type 2 diabetes and obesity through comprehensive regulatory restrictions on phthalate use in China.” One Earth, vol. 5, no. 4, Apr. 2022, pp. 380–91. Scopus, doi:10.1016/j.oneear.2022.03.013.

Published In

One Earth

DOI

EISSN

2590-3322

ISSN

2590-3330

Publication Date

April 15, 2022

Volume

5

Issue

4

Start / End Page

380 / 391

Related Subject Headings

  • 41 Environmental sciences
  • 37 Earth sciences