Scholars@Duke publication: Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.

Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.

Publication , Journal Article

Zullig, LL; Peterson, ED; Shah, BR; Grambow, SC; Oddone, EZ; McCant, F; Lindquist, JH; Bosworth, HB

Published in: Patient Educ Couns

September 2022

Published version (DOI) Open Access Copy (Duke) Link to item

OBJECTIVE: We evaluated the impact of a low intensity web-based and intensive nurse-administered intervention to reduce systolic blood pressure (SBP) among patients with prior MI. METHODS: Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE) was a three-arm trial. Patients were randomized to 1) post-MI education-only; 2) nurse-administered telephone program; or 3) web-based interactive tool. The study was conducted 2009-2013. RESULTS: Participants (n = 415) had a mean age of 61 years (standard deviation [SD], 11). Relative to the education-only group, the 12-month differential improvement in SBP was - 3.97 and - 3.27 mmHg for nurse-administered telephone and web-based groups, respectively. Neither were statistically significant. Post hoc exploratory subgroup analyses found participants who received a higher dose (>12 encounters) in the nurse-administered telephone intervention (n = 60; 46%) had an 8.8 mmHg (95% CI, 0.69, 16.89; p = 0.03) differential SBP improvement versus low dose (<11 encounters; n = 71; 54%). For the web-based intervention, those who had higher dose (n = 73; 53%; >1 web encounter) experienced a 2.3 mmHg (95% CI, -10.74, 6.14; p = 0.59) differential SBP improvement versus low dose (n = 65; 47%). CONCLUSIONS: The main effects were not statistically significant. PRACTICAL IMPLICATIONS: Completing the full dose of the intervention may be essential to experience the intervention effect. CLINICAL TRIAL REGISTRATION: The unique identifier is NCT00901277 (http://www. CLINICALTRIALS: gov/ct2/show/NCT00901277?term=NCT00901277&rank=1).

Duke Scholars

Author Leah L Zullig Population Health Sciences

Author Steven C. Grambow Biostatistics & Bioinformatics, Division of Biostatistics

Author Eugene Zaverio Oddone Medicine, General Internal Medicine

Author Hayden Barry Bosworth Population Health Sciences

Published In

Patient Educ Couns

DOI

10.1016/j.pec.2022.05.011

EISSN

1873-5134

Publication Date

September 2022

Volume

105

Issue

Start / End Page

2962 / 2968

Location

Ireland

Related Subject Headings

Telemedicine
Secondary Prevention
Public Health
Patient Education as Topic
Myocardial Infarction
Middle Aged
Humans
Blood Pressure
4203 Health services and systems
17 Psychology and Cognitive Sciences

Citation

APA

Chicago

ICMJE

MLA

NLM

Zullig, L. L., Peterson, E. D., Shah, B. R., Grambow, S. C., Oddone, E. Z., McCant, F., … Bosworth, H. B. (2022). Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management. Patient Educ Couns, 105(9), 2962–2968. https://doi.org/10.1016/j.pec.2022.05.011

Zullig, Leah L., Eric D. Peterson, Bimal R. Shah, Steven C. Grambow, Eugene Z. Oddone, Felicia McCant, Jennifer Hoff Lindquist, and Hayden B. Bosworth. “Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.” Patient Educ Couns 105, no. 9 (September 2022): 2962–68. https://doi.org/10.1016/j.pec.2022.05.011.

Zullig LL, Peterson ED, Shah BR, Grambow SC, Oddone EZ, McCant F, et al. Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management. Patient Educ Couns. 2022 Sep;105(9):2962–8.

Zullig, Leah L., et al. “Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management.” Patient Educ Couns, vol. 105, no. 9, Sept. 2022, pp. 2962–68. Pubmed, doi:10.1016/j.pec.2022.05.011.

Zullig LL, Peterson ED, Shah BR, Grambow SC, Oddone EZ, McCant F, Lindquist JH, Bosworth HB. Secondary Prevention Risk Interventions via Telemedicine and Tailored Patient Education (SPRITE): A randomized trial to improve post myocardial infarction management. Patient Educ Couns. 2022 Sep;105(9):2962–2968.