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Breaking barriers in postoperative delirium.

Publication ,  Journal Article
Terrando, N; Akassoglou, K
Published in: Br J Anaesth
August 2022

Systemic perturbations such as peripheral surgical trauma induce neurovascular, inflammatory, and cognitive changes. The blood-brain barrier is a key interface between the periphery and the central nervous system, and is critically involved in regulating neuroimmune interactions to maintain overall homeostasis. Mounting evidence suggests that blood-brain barrier dysfunction is a hallmark of ageing and multiple neurological conditions including Alzheimer's disease. We discuss a recent study published in the British Journal of Anaesthesia that describes blood-brain barrier changes and neuroinflammation in patients with postoperative delirium after non-intracranial surgery.

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Published In

Br J Anaesth

DOI

EISSN

1471-6771

Publication Date

August 2022

Volume

129

Issue

2

Start / End Page

147 / 150

Location

England

Related Subject Headings

  • Neuroimmunomodulation
  • Humans
  • Delirium
  • Central Nervous System
  • Blood-Brain Barrier
  • Anesthesiology
  • Alzheimer Disease
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Terrando, N., & Akassoglou, K. (2022). Breaking barriers in postoperative delirium. Br J Anaesth, 129(2), 147–150. https://doi.org/10.1016/j.bja.2022.05.004
Terrando, Niccolò, and Katerina Akassoglou. “Breaking barriers in postoperative delirium.Br J Anaesth 129, no. 2 (August 2022): 147–50. https://doi.org/10.1016/j.bja.2022.05.004.
Terrando N, Akassoglou K. Breaking barriers in postoperative delirium. Br J Anaesth. 2022 Aug;129(2):147–50.
Terrando, Niccolò, and Katerina Akassoglou. “Breaking barriers in postoperative delirium.Br J Anaesth, vol. 129, no. 2, Aug. 2022, pp. 147–50. Pubmed, doi:10.1016/j.bja.2022.05.004.
Terrando N, Akassoglou K. Breaking barriers in postoperative delirium. Br J Anaesth. 2022 Aug;129(2):147–150.
Journal cover image

Published In

Br J Anaesth

DOI

EISSN

1471-6771

Publication Date

August 2022

Volume

129

Issue

2

Start / End Page

147 / 150

Location

England

Related Subject Headings

  • Neuroimmunomodulation
  • Humans
  • Delirium
  • Central Nervous System
  • Blood-Brain Barrier
  • Anesthesiology
  • Alzheimer Disease
  • 3202 Clinical sciences
  • 1103 Clinical Sciences