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Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group.

Publication ,  Journal Article
Yassine, HN; Samieri, C; Livingston, G; Glass, K; Wagner, M; Tangney, C; Plassman, BL; Ikram, MA; Voigt, RM; Gu, Y; O'Bryant, S; Minihane, AM ...
Published in: Lancet Healthy Longev
July 2022

Observational studies suggest that nutritional factors have a potential cognitive benefit. However, systematic reviews of randomised trials of dietary and nutritional supplements have reported largely null effects on cognitive outcomes and have highlighted study inconsistencies and other limitations. In this Personal View, the Nutrition for Dementia Prevention Working Group presents what we consider to be limitations in the existing nutrition clinical trials for dementia prevention. On the basis of this evidence, we propose recommendations for incorporating dietary patterns and the use of genetic, and nutrition assessment tools, biomarkers, and novel clinical trial designs to guide future trial developments. Nutrition-based research has unique challenges that could require testing both more personalised interventions in targeted risk subgroups, identified by nutritional and other biomarkers, and large-scale and pragmatic study designs for more generalisable public health interventions across diverse populations.

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Published In

Lancet Healthy Longev

DOI

EISSN

2666-7568

Publication Date

July 2022

Volume

3

Issue

7

Start / End Page

e501 / e512

Location

England

Related Subject Headings

  • Nutritional Status
  • Humans
  • Dietary Supplements
  • Diet
  • Dementia
  • Biomarkers
  • 4206 Public health
  • 4202 Epidemiology
 

Citation

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Yassine, H. N., Samieri, C., Livingston, G., Glass, K., Wagner, M., Tangney, C., … Schneider, L. S. (2022). Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group. Lancet Healthy Longev, 3(7), e501–e512. https://doi.org/10.1016/s2666-7568(22)00120-9
Yassine, Hussein N., Cécilia Samieri, Gill Livingston, Kimberly Glass, Maude Wagner, Christy Tangney, Brenda L. Plassman, et al. “Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group.Lancet Healthy Longev 3, no. 7 (July 2022): e501–12. https://doi.org/10.1016/s2666-7568(22)00120-9.
Yassine HN, Samieri C, Livingston G, Glass K, Wagner M, Tangney C, et al. Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group. Lancet Healthy Longev. 2022 Jul;3(7):e501–12.
Yassine, Hussein N., et al. “Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group.Lancet Healthy Longev, vol. 3, no. 7, July 2022, pp. e501–12. Pubmed, doi:10.1016/s2666-7568(22)00120-9.
Yassine HN, Samieri C, Livingston G, Glass K, Wagner M, Tangney C, Plassman BL, Ikram MA, Voigt RM, Gu Y, O’Bryant S, Minihane AM, Craft S, Fink HA, Judd S, Andrieu S, Bowman GL, Richard E, Albensi B, Meyers E, Khosravian S, Solis M, Carrillo M, Snyder H, Grodstein F, Scarmeas N, Schneider LS. Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group. Lancet Healthy Longev. 2022 Jul;3(7):e501–e512.

Published In

Lancet Healthy Longev

DOI

EISSN

2666-7568

Publication Date

July 2022

Volume

3

Issue

7

Start / End Page

e501 / e512

Location

England

Related Subject Headings

  • Nutritional Status
  • Humans
  • Dietary Supplements
  • Diet
  • Dementia
  • Biomarkers
  • 4206 Public health
  • 4202 Epidemiology