Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.
Publication
, Journal Article
Gao, C; Wang, Y
Published in: Circ J
2014
With the advancement of transcriptome profiling by micro-arrays and high-throughput RNA-sequencing, transcriptome complexity and its dynamics are revealed at different levels in cardiovascular development and diseases. In this review, we will highlight the recent progress in our knowledge of cardiovascular transcriptome complexity contributed by RNA splicing, RNA editing and noncoding RNAs. The emerging importance of many of these previously under-explored aspects of gene regulation in cardiovascular development and pathology will be discussed.
Duke Scholars
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Published In
Circ J
DOI
EISSN
1347-4820
Publication Date
2014
Volume
78
Issue
5
Start / End Page
1038 / 1047
Location
Japan
Related Subject Headings
- Transcriptome
- RNA, Untranslated
- RNA Splicing
- RNA Editing
- Humans
- Heart Diseases
- Heart
- Gene Expression Regulation, Developmental
- Cardiovascular System & Hematology
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Gao, C., & Wang, Y. (2014). Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J, 78(5), 1038–1047. https://doi.org/10.1253/circj.cj-14-0412
Gao, Chen, and Yibin Wang. “Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.” Circ J 78, no. 5 (2014): 1038–47. https://doi.org/10.1253/circj.cj-14-0412.
Gao C, Wang Y. Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J. 2014;78(5):1038–47.
Gao, Chen, and Yibin Wang. “Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.” Circ J, vol. 78, no. 5, 2014, pp. 1038–47. Pubmed, doi:10.1253/circj.cj-14-0412.
Gao C, Wang Y. Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J. 2014;78(5):1038–1047.
Published In
Circ J
DOI
EISSN
1347-4820
Publication Date
2014
Volume
78
Issue
5
Start / End Page
1038 / 1047
Location
Japan
Related Subject Headings
- Transcriptome
- RNA, Untranslated
- RNA Splicing
- RNA Editing
- Humans
- Heart Diseases
- Heart
- Gene Expression Regulation, Developmental
- Cardiovascular System & Hematology
- Animals