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Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.

Publication ,  Journal Article
Gao, C; Wang, Y
Published in: Circ J
2014

With the advancement of transcriptome profiling by micro-arrays and high-throughput RNA-sequencing, transcriptome complexity and its dynamics are revealed at different levels in cardiovascular development and diseases. In this review, we will highlight the recent progress in our knowledge of cardiovascular transcriptome complexity contributed by RNA splicing, RNA editing and noncoding RNAs. The emerging importance of many of these previously under-explored aspects of gene regulation in cardiovascular development and pathology will be discussed.

Duke Scholars

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Published In

Circ J

DOI

EISSN

1347-4820

Publication Date

2014

Volume

78

Issue

5

Start / End Page

1038 / 1047

Location

Japan

Related Subject Headings

  • Transcriptome
  • RNA, Untranslated
  • RNA Splicing
  • RNA Editing
  • Humans
  • Heart Diseases
  • Heart
  • Gene Expression Regulation, Developmental
  • Cardiovascular System & Hematology
  • Animals
 

Citation

APA
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ICMJE
MLA
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Gao, C., & Wang, Y. (2014). Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J, 78(5), 1038–1047. https://doi.org/10.1253/circj.cj-14-0412
Gao, Chen, and Yibin Wang. “Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.Circ J 78, no. 5 (2014): 1038–47. https://doi.org/10.1253/circj.cj-14-0412.
Gao, Chen, and Yibin Wang. “Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome.Circ J, vol. 78, no. 5, 2014, pp. 1038–47. Pubmed, doi:10.1253/circj.cj-14-0412.

Published In

Circ J

DOI

EISSN

1347-4820

Publication Date

2014

Volume

78

Issue

5

Start / End Page

1038 / 1047

Location

Japan

Related Subject Headings

  • Transcriptome
  • RNA, Untranslated
  • RNA Splicing
  • RNA Editing
  • Humans
  • Heart Diseases
  • Heart
  • Gene Expression Regulation, Developmental
  • Cardiovascular System & Hematology
  • Animals