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Adenovirus technology for gene manipulation and functional studies.

Publication ,  Journal Article
Wang, I; Huang, I
Published in: Drug Discov Today
January 2000

Recombinant adenoviral vectors are highly efficient at gene transfer in a broad spectrum of cell types and species, and have been used, both in vitro and in vivo, to achieve gain or loss of function in functional studies. In recent years, there have been several significant advances in adenovirus technologies, including new generations of vectors, improved production systems and sophisticated methods of delivery. In this review, recent progress and innovative applications are discussed to demonstrate the potential of the recombinant adenoviral vector as an effective tool in functional genomics.

Duke Scholars

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Published In

Drug Discov Today

DOI

EISSN

1878-5832

Publication Date

January 2000

Volume

5

Issue

1

Start / End Page

10 / 16

Location

England

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0601 Biochemistry and Cell Biology
 

Citation

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Wang, I., & Huang, I. (2000). Adenovirus technology for gene manipulation and functional studies. Drug Discov Today, 5(1), 10–16. https://doi.org/10.1016/s1359-6446(99)01433-6
Wang, I., and I. Huang. “Adenovirus technology for gene manipulation and functional studies.Drug Discov Today 5, no. 1 (January 2000): 10–16. https://doi.org/10.1016/s1359-6446(99)01433-6.
Wang I, Huang I. Adenovirus technology for gene manipulation and functional studies. Drug Discov Today. 2000 Jan;5(1):10–6.
Wang, I., and I. Huang. “Adenovirus technology for gene manipulation and functional studies.Drug Discov Today, vol. 5, no. 1, Jan. 2000, pp. 10–16. Pubmed, doi:10.1016/s1359-6446(99)01433-6.
Wang I, Huang I. Adenovirus technology for gene manipulation and functional studies. Drug Discov Today. 2000 Jan;5(1):10–16.
Journal cover image

Published In

Drug Discov Today

DOI

EISSN

1878-5832

Publication Date

January 2000

Volume

5

Issue

1

Start / End Page

10 / 16

Location

England

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0601 Biochemistry and Cell Biology