Skip to main content
Journal cover image

Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury.

Publication ,  Journal Article
Chaiwat, O; Vavilala, MS; Philip, S; Malakouti, A; Neff, MJ; Deem, S; Treggiari, MM; Wang, J; Lang, JD
Published in: J Crit Care
April 2011

PURPOSE: Low tidal volume (LTV) ventilation reduces mortality in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). This study investigates adherence of intraoperative LTV and whether patient outcomes were different with or without continued intraoperative LTV ventilation in patients with previously established ALI or ARDS. MATERIALS AND METHODS: A retrospective analysis was performed of adults with ALI/ARDS over a 2-year period who underwent surgery between 24 hours and 14 days after the diagnosis of ALI/ARDS. The main outcome was intraoperative LTV use. Secondary outcomes included perioperative respiratory and clinical outcomes. RESULTS: Of the 249 patients who underwent surgery between 24 hours and 14 days after ALI/ARDS diagnosis, 101 (41%) received preoperative LTV ventilation. Fifty-four (53%) received intraoperative LTV ventilation, whereas 47 (47%) did not. Use of preoperative LTV ventilation was associated with use of intraoperative LTV ventilation (P < .01). No differences in respiratory or clinical outcomes between patients with or without intraoperative LTV ventilation were observed. CONCLUSIONS: Adherence to intraoperative LTV in surgical patients was low. Adherence of LTV intraoperatively was not associated with improved oxygenation, reductions in hospital length of stay, or in-hospital mortality. The importance of adhering to an intraoperative LTV strategy remains unclear.

Duke Scholars

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

April 2011

Volume

26

Issue

2

Start / End Page

144 / 151

Location

United States

Related Subject Headings

  • Young Adult
  • Tidal Volume
  • Risk Factors
  • Retrospective Studies
  • Practice Guidelines as Topic
  • Positive-Pressure Respiration
  • Middle Aged
  • Male
  • Length of Stay
  • Intraoperative Period
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chaiwat, O., Vavilala, M. S., Philip, S., Malakouti, A., Neff, M. J., Deem, S., … Lang, J. D. (2011). Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. J Crit Care, 26(2), 144–151. https://doi.org/10.1016/j.jcrc.2010.08.002
Chaiwat, Onuma, Monica S. Vavilala, Shaji Philip, Amin Malakouti, Margaret J. Neff, Steven Deem, Miriam M. Treggiari, Jin Wang, and John D. Lang. “Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury.J Crit Care 26, no. 2 (April 2011): 144–51. https://doi.org/10.1016/j.jcrc.2010.08.002.
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, et al. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. J Crit Care. 2011 Apr;26(2):144–51.
Chaiwat, Onuma, et al. “Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury.J Crit Care, vol. 26, no. 2, Apr. 2011, pp. 144–51. Pubmed, doi:10.1016/j.jcrc.2010.08.002.
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, Treggiari MM, Wang J, Lang JD. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. J Crit Care. 2011 Apr;26(2):144–151.
Journal cover image

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

April 2011

Volume

26

Issue

2

Start / End Page

144 / 151

Location

United States

Related Subject Headings

  • Young Adult
  • Tidal Volume
  • Risk Factors
  • Retrospective Studies
  • Practice Guidelines as Topic
  • Positive-Pressure Respiration
  • Middle Aged
  • Male
  • Length of Stay
  • Intraoperative Period