Skip to main content

Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018).

Publication ,  Journal Article
Islam, JY; Nogueira, L; Suneja, G; Coghill, A; Akinyemiju, T
Published in: JCO Oncol Pract
October 2022

PURPOSE: People living with HIV (PLWH) diagnosed with cancer are less likely to receive quality cancer treatment compared with HIV-negative patients. Timely provision of palliative care (PC) during cancer treatment can increase patient's survival and improve quality of life. Our objective was to compare the use of PC by HIV status among adults diagnosed with cancer in the United States. METHODS: More than 19 million individuals age 18-90 years diagnosed with the 11 most common cancers among PLWH were selected from the National Cancer Database (2004-2018). The National Cancer Database defined PC as any surgery, radiation, systemic therapy, or pain management treatment with noncurative intent. Multivariable logistic regression was used to examine associations between HIV status and PC receipt by cancer site and stage after adjustment for covariates. RESULTS: The study population included 52,306 HIV-positive (average age: 56.5 years) and 19,115,520 HIV-negative (average age: 63.7 years) cancer cases. PLWH diagnosed with stage I-III cancer were more likely to receive PC compared with their HIV-negative counterparts (adjusted odds ratio [aO]: 1.96; 95% CI, 1.80 to 2.14); however, they were also less likely to receive curative cancer treatment (aOR, 0.48; 95% CI, 0.40 to 0.59). PLWH diagnosed with stage IV cancer were less likely to receive PC (aOR, 0.70; 95% CI, 0.66 to 0.74) compared with HIV-negative patients. When evaluated by cancer site, PLWH diagnosed with stage IV lung (aOR, 0.80; 95% CI, 0.73 to 0.87) and colorectal (aOR, 0.72, 95% CI, 0.54 to 0.95) cancers were less likely to receive PC than HIV-negative patients. CONCLUSION: PLWH diagnosed with stage IV cancer, particularly lung and colorectal cancers, were less likely to receive PC compared with cancer patients without HIV. PLWH with nonmetastatic disease were more likely to receive PC but less likely to receive curative treatment, reinforcing that clinical strategies are needed to improve the quality of care among PLWH.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

JCO Oncol Pract

DOI

EISSN

2688-1535

Publication Date

October 2022

Volume

18

Issue

10

Start / End Page

e1683 / e1693

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Quality of Life
  • Palliative Care
  • Odds Ratio
  • Neoplasms
  • Middle Aged
  • Humans
  • HIV Infections
  • Aged, 80 and over
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Islam, J. Y., Nogueira, L., Suneja, G., Coghill, A., & Akinyemiju, T. (2022). Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018). JCO Oncol Pract, 18(10), e1683–e1693. https://doi.org/10.1200/OP.22.00181
Islam, Jessica Y., Leticia Nogueira, Gita Suneja, Anna Coghill, and Tomi Akinyemiju. “Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018).JCO Oncol Pract 18, no. 10 (October 2022): e1683–93. https://doi.org/10.1200/OP.22.00181.
Islam JY, Nogueira L, Suneja G, Coghill A, Akinyemiju T. Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018). JCO Oncol Pract. 2022 Oct;18(10):e1683–93.
Islam, Jessica Y., et al. “Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018).JCO Oncol Pract, vol. 18, no. 10, Oct. 2022, pp. e1683–93. Pubmed, doi:10.1200/OP.22.00181.
Islam JY, Nogueira L, Suneja G, Coghill A, Akinyemiju T. Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018). JCO Oncol Pract. 2022 Oct;18(10):e1683–e1693.

Published In

JCO Oncol Pract

DOI

EISSN

2688-1535

Publication Date

October 2022

Volume

18

Issue

10

Start / End Page

e1683 / e1693

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Quality of Life
  • Palliative Care
  • Odds Ratio
  • Neoplasms
  • Middle Aged
  • Humans
  • HIV Infections
  • Aged, 80 and over