The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial.
Publication
, Journal Article
Upadhya, B; Brubaker, PH; Morgan, TM; Eggebeen, JD; Jao, GT; Stewart, KP; Kitzman, DW
Published in: Am Heart J
July 2018
In older patients (70 ± 7 years) with chronic well-compensated heart failure with preserved ejection and controlled blood pressure, 6 months treatment with aliskiren (direct renin inhibitor) showed non-significant trends for modest improvements in peak exercise oxygen consumption (14.9 ± 0.2 mL kg-1 min-1 versus 14.4 ± 0.2 mL kg-1 min-1; P = .10, trend) and ventilatory anaerobic threshold (888 ± 19 mL/min versus 841 ± 18 mL/min; P = .08).
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Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
July 2018
Volume
201
Start / End Page
164 / 167
Location
United States
Related Subject Headings
- Stroke Volume
- Randomized Controlled Trials as Topic
- Male
- Humans
- Heart Failure
- Fumarates
- Female
- Exercise Tolerance
- Double-Blind Method
- Cardiovascular System & Hematology
Citation
APA
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ICMJE
MLA
NLM
Upadhya, B., Brubaker, P. H., Morgan, T. M., Eggebeen, J. D., Jao, G. T., Stewart, K. P., & Kitzman, D. W. (2018). The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial. Am Heart J, 201, 164–167. https://doi.org/10.1016/j.ahj.2018.03.019
Upadhya, Bharathi, Peter H. Brubaker, Timothy M. Morgan, Joel D. Eggebeen, Geoffrey T. Jao, Kathryn P. Stewart, and Dalane W. Kitzman. “The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial.” Am Heart J 201 (July 2018): 164–67. https://doi.org/10.1016/j.ahj.2018.03.019.
Upadhya B, Brubaker PH, Morgan TM, Eggebeen JD, Jao GT, Stewart KP, et al. The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial. Am Heart J. 2018 Jul;201:164–7.
Upadhya, Bharathi, et al. “The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial.” Am Heart J, vol. 201, July 2018, pp. 164–67. Pubmed, doi:10.1016/j.ahj.2018.03.019.
Upadhya B, Brubaker PH, Morgan TM, Eggebeen JD, Jao GT, Stewart KP, Kitzman DW. The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial. Am Heart J. 2018 Jul;201:164–167.
Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
July 2018
Volume
201
Start / End Page
164 / 167
Location
United States
Related Subject Headings
- Stroke Volume
- Randomized Controlled Trials as Topic
- Male
- Humans
- Heart Failure
- Fumarates
- Female
- Exercise Tolerance
- Double-Blind Method
- Cardiovascular System & Hematology