Molecular Mechanisms of Castrate-Resistant Prostate Cancer.
Publication
, Journal Article
Kotamarti, S; Armstrong, AJ; Polascik, TJ; Moul, JW
Published in: Urol Clin North Am
November 2022
Despite newer therapies for castrate-resistant prostate cancer (CRPC), many patients do not experience a treatment response, and most eventually experience secondary resistance. Various androgen-receptor-related and alternative mechanisms of resistance in CRPC have been identified. This focus on understanding the molecular basis of therapeutic resistance, including lineage plasticity, neuroendocrine transformation, and a range of other implicated genomic alterations will hopefully inform decision-making in the care of this lethal cancer.
Duke Scholars
Published In
Urol Clin North Am
DOI
EISSN
1558-318X
Publication Date
November 2022
Volume
49
Issue
4
Start / End Page
615 / 626
Location
United States
Related Subject Headings
- Urology & Nephrology
- Prostatic Neoplasms, Castration-Resistant
- Male
- Humans
- Drug Resistance, Neoplasm
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kotamarti, S., Armstrong, A. J., Polascik, T. J., & Moul, J. W. (2022). Molecular Mechanisms of Castrate-Resistant Prostate Cancer. Urol Clin North Am, 49(4), 615–626. https://doi.org/10.1016/j.ucl.2022.07.005
Kotamarti, Srinath, Andrew J. Armstrong, Thomas J. Polascik, and Judd W. Moul. “Molecular Mechanisms of Castrate-Resistant Prostate Cancer.” Urol Clin North Am 49, no. 4 (November 2022): 615–26. https://doi.org/10.1016/j.ucl.2022.07.005.
Kotamarti S, Armstrong AJ, Polascik TJ, Moul JW. Molecular Mechanisms of Castrate-Resistant Prostate Cancer. Urol Clin North Am. 2022 Nov;49(4):615–26.
Kotamarti, Srinath, et al. “Molecular Mechanisms of Castrate-Resistant Prostate Cancer.” Urol Clin North Am, vol. 49, no. 4, Nov. 2022, pp. 615–26. Pubmed, doi:10.1016/j.ucl.2022.07.005.
Kotamarti S, Armstrong AJ, Polascik TJ, Moul JW. Molecular Mechanisms of Castrate-Resistant Prostate Cancer. Urol Clin North Am. 2022 Nov;49(4):615–626.
Published In
Urol Clin North Am
DOI
EISSN
1558-318X
Publication Date
November 2022
Volume
49
Issue
4
Start / End Page
615 / 626
Location
United States
Related Subject Headings
- Urology & Nephrology
- Prostatic Neoplasms, Castration-Resistant
- Male
- Humans
- Drug Resistance, Neoplasm
- 3202 Clinical sciences
- 1103 Clinical Sciences