Skip to main content
Journal cover image

Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years.

Publication ,  Journal Article
Hernandez, NM; Wu, CJ; Hinton, ZW; Ryan, SP; Bolognesi, MP; Seyler, TM
Published in: Arthroplast Today
December 2022

BACKGROUND: There are few large studies evaluating total knee arthroplasty (TKA) in young patients. Therefore, we sought to evaluate patients aged 45 years or younger undergoing a primary TKA. METHODS: This was a retrospective, single-institution study, from 2003 to 2018, evaluating primary TKA in patients aged 45 years or younger. We identified 162 TKAs with a minimum follow-up duration of 2 years. Common surgical indications were degenerative joint disease (50%), post-traumatic arthritis (21%), and inflammatory arthritis (20%). Forty-nine knees had a prior significant knee surgery. We evaluated survivorship free of revision for any reason and aseptic revision. In addition, we characterized complication rates and risk factors for failure. RESULTS: The mean age was 39 years, 70% were female, and the mean clinical follow-up duration was 7 years. At 8 years, survivorship free of revision for any reason was 82%, and survivorship free of aseptic revision was 87%. Fifty-five knees experienced at least 1 complication, with an overall complication rate of 34%. There were 6 (4%) periprosthetic joint infections (PJIs), and 24 (15%) knees of patients underwent manipulation under anesthesia with or without arthroscopic lysis of adhesions. There were no specific risk factors for revisions identified. Age less than 40 years was associated with PJI (P = .031), and marital status at the time of TKA was associated with arthrofibrosis requiring an intervention (P = .045). CONCLUSIONS: TKAs in patients aged 45 years or younger are associated with acceptable survivorship at a mean follow-up duration of 7 years. Patients should be counseled about the elevated risk of complications, specifically PJI and arthrofibrosis.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Arthroplast Today

DOI

ISSN

2352-3441

Publication Date

December 2022

Volume

18

Start / End Page

163 / 167

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hernandez, N. M., Wu, C. J., Hinton, Z. W., Ryan, S. P., Bolognesi, M. P., & Seyler, T. M. (2022). Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years. Arthroplast Today, 18, 163–167. https://doi.org/10.1016/j.artd.2022.09.018
Hernandez, Nicholas M., Christine J. Wu, Zoe W. Hinton, Sean P. Ryan, Michael P. Bolognesi, and Thorsten M. Seyler. “Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years.Arthroplast Today 18 (December 2022): 163–67. https://doi.org/10.1016/j.artd.2022.09.018.
Hernandez NM, Wu CJ, Hinton ZW, Ryan SP, Bolognesi MP, Seyler TM. Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years. Arthroplast Today. 2022 Dec;18:163–7.
Hernandez, Nicholas M., et al. “Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years.Arthroplast Today, vol. 18, Dec. 2022, pp. 163–67. Pubmed, doi:10.1016/j.artd.2022.09.018.
Hernandez NM, Wu CJ, Hinton ZW, Ryan SP, Bolognesi MP, Seyler TM. Primary Total Knee Arthroplasty in Patients Aged 45 Years or Younger: 162 Total Knee Arthroplasties With a Mean Follow-up Duration of 7 Years. Arthroplast Today. 2022 Dec;18:163–167.
Journal cover image

Published In

Arthroplast Today

DOI

ISSN

2352-3441

Publication Date

December 2022

Volume

18

Start / End Page

163 / 167

Location

United States