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Crystallization of a Complex Between MYC and Jas Motif.

Publication ,  Chapter
Zhang, F; He, SY; Melcher, K
January 2020

In the jasmonate signaling pathway, a region of 17 amino acids within the Jas motif of JAZ proteins and a conserved region within the N-terminus of MYC proteins are sufficient for JAZ-MYC interactions. Crystal structures of Jas-MYC complexes have revealed the structural basis of this important interaction. Here, we describe methods of cloning, expression, and purification of MYC N-terminal proteins and their co-crystallization with Jas motif peptides.

Duke Scholars

DOI

Publication Date

January 2020

Volume

2085

Start / End Page

133 / 144

Related Subject Headings

  • Repressor Proteins
  • Recombinant Proteins
  • Proto-Oncogene Proteins c-myc
  • Multiprotein Complexes
  • Gene Expression
  • Developmental Biology
  • Crystallization
  • Cloning, Molecular
  • Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
  • Arabidopsis
 

Citation

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Zhang, F., He, S. Y., & Melcher, K. (2020). Crystallization of a Complex Between MYC and Jas Motif. (Vol. 2085, pp. 133–144). https://doi.org/10.1007/978-1-0716-0142-6_10
Zhang, Feng, Sheng Yang He, and Karsten Melcher. “Crystallization of a Complex Between MYC and Jas Motif.,” 2085:133–44, 2020. https://doi.org/10.1007/978-1-0716-0142-6_10.
Zhang F, He SY, Melcher K. Crystallization of a Complex Between MYC and Jas Motif. In 2020. p. 133–44.
Zhang, Feng, et al. Crystallization of a Complex Between MYC and Jas Motif. Vol. 2085, 2020, pp. 133–44. Epmc, doi:10.1007/978-1-0716-0142-6_10.
Zhang F, He SY, Melcher K. Crystallization of a Complex Between MYC and Jas Motif. 2020. p. 133–144.

DOI

Publication Date

January 2020

Volume

2085

Start / End Page

133 / 144

Related Subject Headings

  • Repressor Proteins
  • Recombinant Proteins
  • Proto-Oncogene Proteins c-myc
  • Multiprotein Complexes
  • Gene Expression
  • Developmental Biology
  • Crystallization
  • Cloning, Molecular
  • Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
  • Arabidopsis