
State-of-the-art of regulatory dendritic cells in cancer.
Publication
, Journal Article
Conejo-Garcia, JR; Rutkowski, MR; Cubillos-Ruiz, JR
Published in: Pharmacol Ther
August 2016
Dendritic cells (DCs) with robust immunosuppressive activity are commonly found in the microenvironment of advanced solid tumors. These innate immune cells are generically termed regulatory DCs and include various subsets such as plasmacytoid, conventional and monocyte-derived/inflammatory populations whose normal function is subverted by tumor-derived signals. This review summarizes recent findings on the nature and function of regulatory DCs, their relationship with other myeloid subsets and unique therapeutic opportunities to abrogate malignant progression through their targeting.
Duke Scholars
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Published In
Pharmacol Ther
DOI
EISSN
1879-016X
Publication Date
August 2016
Volume
164
Start / End Page
97 / 104
Location
England
Related Subject Headings
- Transforming Growth Factor beta
- Pharmacology & Pharmacy
- Neoplasms
- Nanostructures
- Myelopoiesis
- Matrix Attachment Region Binding Proteins
- Macrophages
- Immune Tolerance
- Humans
- Dinoprostone
Citation
APA
Chicago
ICMJE
MLA
NLM
Conejo-Garcia, J. R., Rutkowski, M. R., & Cubillos-Ruiz, J. R. (2016). State-of-the-art of regulatory dendritic cells in cancer. Pharmacol Ther, 164, 97–104. https://doi.org/10.1016/j.pharmthera.2016.04.003
Conejo-Garcia, Jose R., Melanie R. Rutkowski, and Juan R. Cubillos-Ruiz. “State-of-the-art of regulatory dendritic cells in cancer.” Pharmacol Ther 164 (August 2016): 97–104. https://doi.org/10.1016/j.pharmthera.2016.04.003.
Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. State-of-the-art of regulatory dendritic cells in cancer. Pharmacol Ther. 2016 Aug;164:97–104.
Conejo-Garcia, Jose R., et al. “State-of-the-art of regulatory dendritic cells in cancer.” Pharmacol Ther, vol. 164, Aug. 2016, pp. 97–104. Pubmed, doi:10.1016/j.pharmthera.2016.04.003.
Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. State-of-the-art of regulatory dendritic cells in cancer. Pharmacol Ther. 2016 Aug;164:97–104.

Published In
Pharmacol Ther
DOI
EISSN
1879-016X
Publication Date
August 2016
Volume
164
Start / End Page
97 / 104
Location
England
Related Subject Headings
- Transforming Growth Factor beta
- Pharmacology & Pharmacy
- Neoplasms
- Nanostructures
- Myelopoiesis
- Matrix Attachment Region Binding Proteins
- Macrophages
- Immune Tolerance
- Humans
- Dinoprostone