Skip to main content
Journal cover image

History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022.

Publication ,  Journal Article
Tator, CH; Guest, JD; Neal, CJ; Howley, SP; Toups, EG; Harrop, JS; Aarabi, B; Shaffrey, CI; Fehlings, MG
Published in: J Neurotrauma
September 2023

This is a historical account of the origin and accomplishments of the North American Clinical Trials Network (NACTN) for traumatic spinal cord injury (SCI), which was established in 2004 by Christopher Reeve and Robert Grossman. Christopher Reeve was an actor who became quadriplegic and started the Christopher & Dana Reeve Foundation (CDRF), and Robert Grossman was a neurosurgeon experienced in neurotrauma and a university professor in Houston. NACTN has member investigators at university and military centers in North America and has contributed greatly to the improvement of care, primarily acute care, of patients sustaining traumatic SCI. Its accomplishments are a clinical registry database of >1000 acute SCI patients documenting the care pathways, including complications. NACTN has assessed the effectiveness of treatment, including pharmacotherapy and the role and timing of surgery, and has also identified barriers to early surgery. The principal focus has been on improving neurological recovery. NACTN has trained many SCI practitioners and has collaborated with other SCI networks and organizations internationally to promote the care of SCI patients.

Duke Scholars

Published In

J Neurotrauma

DOI

EISSN

1557-9042

Publication Date

September 2023

Volume

40

Issue

17-18

Start / End Page

1823 / 1833

Location

United States

Related Subject Headings

  • Spinal Cord Injuries
  • Spinal Cord
  • Registries
  • North America
  • Neurology & Neurosurgery
  • Humans
  • Clinical Trials as Topic
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tator, C. H., Guest, J. D., Neal, C. J., Howley, S. P., Toups, E. G., Harrop, J. S., … Fehlings, M. G. (2023). History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022. J Neurotrauma, 40(17–18), 1823–1833. https://doi.org/10.1089/neu.2022.0404
Tator, Charles H., James D. Guest, Chris J. Neal, Susan P. Howley, Elizabeth G. Toups, James S. Harrop, Bizhan Aarabi, Christopher I. Shaffrey, and Michael G. Fehlings. “History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022.J Neurotrauma 40, no. 17–18 (September 2023): 1823–33. https://doi.org/10.1089/neu.2022.0404.
Tator CH, Guest JD, Neal CJ, Howley SP, Toups EG, Harrop JS, et al. History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022. J Neurotrauma. 2023 Sep;40(17–18):1823–33.
Tator, Charles H., et al. “History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022.J Neurotrauma, vol. 40, no. 17–18, Sept. 2023, pp. 1823–33. Pubmed, doi:10.1089/neu.2022.0404.
Tator CH, Guest JD, Neal CJ, Howley SP, Toups EG, Harrop JS, Aarabi B, Shaffrey CI, Fehlings MG. History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022. J Neurotrauma. 2023 Sep;40(17–18):1823–1833.
Journal cover image

Published In

J Neurotrauma

DOI

EISSN

1557-9042

Publication Date

September 2023

Volume

40

Issue

17-18

Start / End Page

1823 / 1833

Location

United States

Related Subject Headings

  • Spinal Cord Injuries
  • Spinal Cord
  • Registries
  • North America
  • Neurology & Neurosurgery
  • Humans
  • Clinical Trials as Topic
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 3202 Clinical sciences