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Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases.

Publication ,  Journal Article
Handelsman, Y; Butler, J; Bakris, GL; DeFronzo, RA; Fonarow, GC; Green, JB; Grunberger, G; Januzzi, JL; Klein, S; Kushner, PR; McGuire, DK ...
Published in: J Diabetes Complications
February 2023

Increasing rates of obesity and diabetes have driven corresponding increases in related cardiorenal and metabolic diseases. In many patients, these conditions occur together, further increasing morbidity and mortality risks to the individual. Yet all too often, the risk factors for these disorders are not addressed promptly in clinical practice, leading to irreversible pathologic progression. To address this gap, we convened a Task Force of experts in cardiology, nephrology, endocrinology, and primary care to develop recommendations for early identification and intervention in obesity, diabetes, and other cardiorenal and metabolic diseases. The recommendations include screening and diagnosis, early interventions with lifestyle, and when and how to implement medical therapies. These recommendations are organized into primary and secondary prevention along the continuum from obesity through the metabolic syndrome, prediabetes, diabetes, hypertension, dyslipidemia, nonalcoholic fatty liver disease (NAFLD), atherosclerotic cardiovascular disease (ASCVD) and atrial fibrillation, chronic kidney disease (CKD), and heart failure (HF). The goal of early and intensive intervention is primary prevention of comorbidities or secondary prevention to decrease further worsening of disease and reduce morbidity and mortality. These efforts will reduce clinical inertia and may improve patients' well-being and adherence.

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Published In

J Diabetes Complications

DOI

EISSN

1873-460X

Publication Date

February 2023

Volume

37

Issue

2

Start / End Page

108389

Location

United States

Related Subject Headings

  • Risk Factors
  • Obesity
  • Hypertension
  • Humans
  • Endocrinology & Metabolism
  • Diabetes Mellitus
  • Comorbidity
  • Cardiovascular Diseases
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Handelsman, Y., Butler, J., Bakris, G. L., DeFronzo, R. A., Fonarow, G. C., Green, J. B., … Fonseca, V. A. (2023). Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases. J Diabetes Complications, 37(2), 108389. https://doi.org/10.1016/j.jdiacomp.2022.108389
Handelsman, Yehuda, Javed Butler, George L. Bakris, Ralph A. DeFronzo, Gregg C. Fonarow, Jennifer B. Green, George Grunberger, et al. “Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases.J Diabetes Complications 37, no. 2 (February 2023): 108389. https://doi.org/10.1016/j.jdiacomp.2022.108389.
Handelsman Y, Butler J, Bakris GL, DeFronzo RA, Fonarow GC, Green JB, et al. Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases. J Diabetes Complications. 2023 Feb;37(2):108389.
Handelsman, Yehuda, et al. “Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases.J Diabetes Complications, vol. 37, no. 2, Feb. 2023, p. 108389. Pubmed, doi:10.1016/j.jdiacomp.2022.108389.
Handelsman Y, Butler J, Bakris GL, DeFronzo RA, Fonarow GC, Green JB, Grunberger G, Januzzi JL, Klein S, Kushner PR, McGuire DK, Michos ED, Morales J, Pratley RE, Weir MR, Wright E, Fonseca VA. Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases. J Diabetes Complications. 2023 Feb;37(2):108389.
Journal cover image

Published In

J Diabetes Complications

DOI

EISSN

1873-460X

Publication Date

February 2023

Volume

37

Issue

2

Start / End Page

108389

Location

United States

Related Subject Headings

  • Risk Factors
  • Obesity
  • Hypertension
  • Humans
  • Endocrinology & Metabolism
  • Diabetes Mellitus
  • Comorbidity
  • Cardiovascular Diseases
  • 3202 Clinical sciences
  • 1103 Clinical Sciences