Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021.
Publication
, Journal Article
Lewis, NM; Naioti, EA; Self, WH; Ginde, AA; Douin, DJ; Keipp Talbot, H; Casey, JD; Mohr, NM; Zepeski, A; Gaglani, M; Ghamande, SA; McNeal, TA ...
Published in: J Infect Dis
May 16, 2022
Vaccine effectiveness (VE) against COVID-19 hospitalization was evaluated among immunocompetent adults (≥18 years) during March-August 2021 using a case-control design. Among 1669 hospitalized COVID-19 cases (11% fully vaccinated) and 1950 RT-PCR-negative controls (54% fully vaccinated), VE was 96% (95% confidence interval [CI], 93%-98%) among patients with no chronic medical conditions and 83% (95% CI, 76%-88%) among patients with ≥ 3 categories of conditions. VE was similar between those aged 18-64 years versus ≥65 years (P > .05). VE against severe COVID-19 was very high among adults without chronic conditions and lessened with increasing comorbidity burden.
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Published In
J Infect Dis
DOI
EISSN
1537-6613
Publication Date
May 16, 2022
Volume
225
Issue
10
Start / End Page
1694 / 1700
Location
United States
Related Subject Headings
- mRNA Vaccines
- Vaccines, Synthetic
- Microbiology
- Humans
- Hospitalization
- Chronic Disease
- COVID-19 Vaccines
- COVID-19
- Adult
- 42 Health sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Lewis, N. M., Naioti, E. A., Self, W. H., Ginde, A. A., Douin, D. J., Keipp Talbot, H., … IVY Network Collaborators. (2022). Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021. J Infect Dis, 225(10), 1694–1700. https://doi.org/10.1093/infdis/jiab619
Lewis, Nathaniel M., Eric A. Naioti, Wesley H. Self, Adit A. Ginde, David J. Douin, H. Keipp Talbot, Jonathan D. Casey, et al. “Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021.” J Infect Dis 225, no. 10 (May 16, 2022): 1694–1700. https://doi.org/10.1093/infdis/jiab619.
Lewis NM, Naioti EA, Self WH, Ginde AA, Douin DJ, Keipp Talbot H, et al. Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021. J Infect Dis. 2022 May 16;225(10):1694–700.
Lewis, Nathaniel M., et al. “Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021.” J Infect Dis, vol. 225, no. 10, May 2022, pp. 1694–700. Pubmed, doi:10.1093/infdis/jiab619.
Lewis NM, Naioti EA, Self WH, Ginde AA, Douin DJ, Keipp Talbot H, Casey JD, Mohr NM, Zepeski A, Gaglani M, Ghamande SA, McNeal TA, Shapiro NI, Gibbs KW, Clark Files D, Hager DN, Shehu A, Prekker ME, Erickson HL, Gong MN, Mohamed A, Henning DJ, Steingrub JS, Peltan ID, Brown SM, Martin ET, Hubel K, Hough CL, Busse LW, Ten Lohuis CC, Duggal A, Wilson JG, Gordon AJ, Qadir N, Chang SY, Mallow C, Rivas C, Babcock HM, Kwon JH, Exline MC, Halasa N, Chappell JD, Lauring AS, Grijalva CG, Rice TW, Rhoads JP, Stubblefield WB, Baughman A, Womack KN, Lindsell CJ, Hart KW, Zhu Y, Schrag SJ, Kobayashi M, Verani JR, Patel MM, Tenforde MW, IVY Network Collaborators. Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021. J Infect Dis. 2022 May 16;225(10):1694–1700.
Published In
J Infect Dis
DOI
EISSN
1537-6613
Publication Date
May 16, 2022
Volume
225
Issue
10
Start / End Page
1694 / 1700
Location
United States
Related Subject Headings
- mRNA Vaccines
- Vaccines, Synthetic
- Microbiology
- Humans
- Hospitalization
- Chronic Disease
- COVID-19 Vaccines
- COVID-19
- Adult
- 42 Health sciences