Regulation of DNA break repair by transcription and RNA.
Publication
, Journal Article
Ouyang, J; Lan, L; Zou, L
Published in: Sci China Life Sci
October 2017
Repair of DNA double-strand breaks (DSBs) via the homologous recombination (HR) pathway is a highly regulated process. A number of proteins that participate in HR are intricately modulated by the cell cycle and chromatin environments of DSBs. Recent studies have revealed a clear impact of transcription on HR in transcribed regions of the genome. Several models have been put forth to explain how the process of transcription and/or its RNA products may influence HR. Here we discuss the results and models from these studies, presenting an emerging view of transcription-coupled DSB repair.
Duke Scholars
Published In
Sci China Life Sci
DOI
EISSN
1869-1889
Publication Date
October 2017
Volume
60
Issue
10
Start / End Page
1081 / 1086
Location
China
Related Subject Headings
- Transcription, Genetic
- RNA
- Plant Biology & Botany
- Models, Genetic
- Humans
- Homologous Recombination
- DNA Repair
- DNA Breaks, Double-Stranded
- DNA
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Ouyang, J., Lan, L., & Zou, L. (2017). Regulation of DNA break repair by transcription and RNA. Sci China Life Sci, 60(10), 1081–1086. https://doi.org/10.1007/s11427-017-9164-1
Ouyang, Jian, Li Lan, and Lee Zou. “Regulation of DNA break repair by transcription and RNA.” Sci China Life Sci 60, no. 10 (October 2017): 1081–86. https://doi.org/10.1007/s11427-017-9164-1.
Ouyang J, Lan L, Zou L. Regulation of DNA break repair by transcription and RNA. Sci China Life Sci. 2017 Oct;60(10):1081–6.
Ouyang, Jian, et al. “Regulation of DNA break repair by transcription and RNA.” Sci China Life Sci, vol. 60, no. 10, Oct. 2017, pp. 1081–86. Pubmed, doi:10.1007/s11427-017-9164-1.
Ouyang J, Lan L, Zou L. Regulation of DNA break repair by transcription and RNA. Sci China Life Sci. 2017 Oct;60(10):1081–1086.
Published In
Sci China Life Sci
DOI
EISSN
1869-1889
Publication Date
October 2017
Volume
60
Issue
10
Start / End Page
1081 / 1086
Location
China
Related Subject Headings
- Transcription, Genetic
- RNA
- Plant Biology & Botany
- Models, Genetic
- Humans
- Homologous Recombination
- DNA Repair
- DNA Breaks, Double-Stranded
- DNA
- Animals