Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis.

Publication ,  Journal Article
Lawson, AB; Kim, J; Johnson, C; Hastert, T; Bandera, EV; Alberg, AJ; Terry, P; Akonde, M; Mandle, H; Cote, ML; Bondy, M; Marks, J; Peres, L ...
Published in: Ann Epidemiol
October 2023

PURPOSE: Deprivation and segregation indices are often examined as possible explanations for observed health disparities in population-based studies. In this study, we assessed the role of recognized deprivation and segregation indices specifically as they affect survival in a cohort of self-identified Black women diagnosed with ovarian cancer who enrolled in the African American Cancer Epidemiology Study. METHODS: Mediation analysis was used to examine the direct and indirect effects between deprivation or segregation and overall survival via a Bayesian structural equation model with Gibbs variable selection. RESULTS: The results suggest that high socioeconomic status-related indices have an association with increased survival, ranging from 25% to 56%. In contrast, index of concentration at the extremes-race does not have a significant impact on overall survival. In many cases, the indirect effects have very wide credible intervals; consequently, the total effect is not well estimated despite the estimation of the direct effect. CONCLUSIONS: Our results show that Black women living in higher socioeconomic status neighborhoods are associated with increased survival with ovarian cancer using area-level economic indices such as Yost or index of concentration at the extremes-income. In addition, the Kolak urbanization index has a similar impact and highlights the importance of area-level deprivation and segregation as potentially modifiable social factors in ovarian cancer survival.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Ann Epidemiol

DOI

EISSN

1873-2585

Publication Date

October 2023

Volume

86

Start / End Page

57 / 64

Location

United States

Related Subject Headings

  • Survival Rate
  • Social Segregation
  • Social Determinants of Health
  • Social Deprivation
  • Ovarian Neoplasms
  • Mediation Analysis
  • Income
  • Humans
  • Health Status Disparities
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lawson, A. B., Kim, J., Johnson, C., Hastert, T., Bandera, E. V., Alberg, A. J., … Peters, E. S. (2023). Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis. Ann Epidemiol, 86, 57–64. https://doi.org/10.1016/j.annepidem.2023.07.001
Lawson, Andrew B., Joanne Kim, Courtney Johnson, Theresa Hastert, Elisa V. Bandera, Anthony J. Alberg, Paul Terry, et al. “Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis.Ann Epidemiol 86 (October 2023): 57–64. https://doi.org/10.1016/j.annepidem.2023.07.001.
Lawson AB, Kim J, Johnson C, Hastert T, Bandera EV, Alberg AJ, et al. Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis. Ann Epidemiol. 2023 Oct;86:57–64.
Lawson, Andrew B., et al. “Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis.Ann Epidemiol, vol. 86, Oct. 2023, pp. 57–64. Pubmed, doi:10.1016/j.annepidem.2023.07.001.
Lawson AB, Kim J, Johnson C, Hastert T, Bandera EV, Alberg AJ, Terry P, Akonde M, Mandle H, Cote ML, Bondy M, Marks J, Peres L, Ratnapradipa KL, Xin Y, Schildkraut J, Peters ES. Deprivation and segregation in ovarian cancer survival among African American women: a mediation analysis. Ann Epidemiol. 2023 Oct;86:57–64.
Journal cover image

Published In

Ann Epidemiol

DOI

EISSN

1873-2585

Publication Date

October 2023

Volume

86

Start / End Page

57 / 64

Location

United States

Related Subject Headings

  • Survival Rate
  • Social Segregation
  • Social Determinants of Health
  • Social Deprivation
  • Ovarian Neoplasms
  • Mediation Analysis
  • Income
  • Humans
  • Health Status Disparities
  • Female